MicroRNAs: Biogenesis and Molecular Functions

Small regulatory RNAs are essential and ubiquitous riboregulators that are the key mediators of RNA interference (RNAi). They include microRNAs (miRNAs) and short‐interfering RNAs (siRNAs), classes of ∼22 nucleotide RNAs. miRNAs and siRNAs bind to Argonaute proteins and form effector complexes that...

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Veröffentlicht in:	Brain pathology (Zurich, Switzerland) Switzerland), 2008-01, Vol.18 (1), p.113-121
Hauptverfasser:	Liu, Xuhang, Fortin, Kristine, Mourelatos, Zissimos
Format:	Artikel
Sprache:	eng
Schlagworte:	Ago Animals Argonaute Argonaute Proteins Dicer Drosophila Proteins - genetics Eukaryotic Initiation Factors Gene Expression Regulation - genetics Humans Macromolecular Substances microRNA MicroRNAs - genetics miRNA miRNP Models, Animal mRNA transcription Protein Biosynthesis - genetics RISC RNA Interference - physiology RNA, Messenger - metabolism RNA, Small Interfering - genetics RNA/intereference RNAi siRNA SYMPOSIUM: MicroRNAs: Biology and Roles in Neurodegeneration and Brain Tumors
Online-Zugang:	Volltext
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