A 57-YEAR-OLD FEMALE WITH A CEREBELLAR MASS

A 57-year-old female presented with recurrent episodes of nausea and vomit, as well as instability during walking. The patient had a history of uterine leiomyosarcoma, for which she underwent a hysterectomy and oophorectomy 8 months ago. CT scan revealed a calcified mass that was located in the left...

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Veröffentlicht in:Brain pathology (Zurich, Switzerland) Switzerland), 2011-05, Vol.21 (3), p.351-354
Hauptverfasser: Venizelos, Ioannis, Anagnostou, Eleftherios, Papathomas, Thomas, Spandos, Vasilios, Marinopoulos, Dimitrios, Tsitsopoulos, Parmenion, Tsonidis, Christos
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container_end_page 354
container_issue 3
container_start_page 351
container_title Brain pathology (Zurich, Switzerland)
container_volume 21
creator Venizelos, Ioannis
Anagnostou, Eleftherios
Papathomas, Thomas
Spandos, Vasilios
Marinopoulos, Dimitrios
Tsitsopoulos, Parmenion
Tsonidis, Christos
description A 57-year-old female presented with recurrent episodes of nausea and vomit, as well as instability during walking. The patient had a history of uterine leiomyosarcoma, for which she underwent a hysterectomy and oophorectomy 8 months ago. CT scan revealed a calcified mass that was located in the left cerebellar hemisphere which was resected. Histologically, multiple tissue fragments displayed infiltration of cerebellar tissue by polymorphic spindle-shaped cells. The Ki-67 proliferation index was approximately 20%. The morphological and immunohistochemical data, in association with the past clinical history, were consistent with cerebellar metastasis of uterine leiomyosarcoma. Although adjuvant radiotherapy was introduced, the patient died of cardiopulmonary arrest 6 weeks after the surgical procedure. The present case adds to the body of literature being the second report of uterine leiomyosarcoma metastatic to the cerebellum.
doi_str_mv 10.1111/j.1750-3639.2011.00483.x
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source MEDLINE; Access via Wiley Online Library; PubMed; EZB Electronic Journals Library
subjects Cerebellar Neoplasms - diagnostic imaging
Cerebellar Neoplasms - radiotherapy
Cerebellar Neoplasms - secondary
Cerebellar Neoplasms - surgery
Correspondence
Fatal Outcome
Female
Humans
Leiomyosarcoma - diagnostic imaging
Leiomyosarcoma - radiotherapy
Leiomyosarcoma - secondary
Leiomyosarcoma - surgery
Middle Aged
Radiography
Uterine Neoplasms - pathology
Uterine Neoplasms - radiotherapy
Uterine Neoplasms - surgery
title A 57-YEAR-OLD FEMALE WITH A CEREBELLAR MASS
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