COVID-19 Vaccine Candidates Based on Modified Vaccinia Virus Ankara Expressing the SARS-CoV-2 Spike Protein Induce Robust T- and B-Cell Immune Responses and Full Efficacy in Mice

Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, are urgently needed. We developed two COVID-19 vaccines based on modified vaccinia virus Ankara (MVA) vectors expressing the entire SARS-CoV-2 spike...

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Veröffentlicht in:	Journal of virology 2021-03, Vol.95 (7)
Hauptverfasser:	García-Arriaza, Juan, Garaigorta, Urtzi, Pérez, Patricia, Lázaro-Frías, Adrián, Zamora, Carmen, Gastaminza, Pablo, del Fresno, Carlos, Casasnovas, José M, S. Sorzano, Carlos Óscar, Sancho, David, Esteban, Mariano
Format:	Artikel
Sprache:	eng
Schlagworte:	Spotlight Vaccines and Antiviral Agents
Online-Zugang:	Volltext
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