Identification of Aristolactam Derivatives That Act as Inhibitors of Human Immunodeficiency Virus Type 1 Infection and Replication by Targeting Tat-Mediated Viral Transcription

Despite the success of antiretroviral therapy (ART), efforts to develop new classes of antiviral agents have been hampered by the emergence of drug resistance. Dibenzo-indole-bearing aristolactams are compounds that have been isolated from various plants species and which show several clinically rel...

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Veröffentlicht in:Virologica Sinica 2021-04, Vol.36 (2), p.254-263
Hauptverfasser: Shin, YoungHyun, Park, Chul Min, Kim, Hong Gi, Kim, Dong-Eun, Choi, Min Suk, Kim, Jeong-ah, Choi, Byeong-Sun, Yoon, Cheol-Hee
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Sprache:eng
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