Integrating blood cell mechanics, platelet adhesive dynamics and coagulation cascade for modelling thrombus formation in normal and diabetic blood

Normal haemostasis is an important physiological mechanism that prevents excessive bleeding during trauma, whereas the pathological thrombosis especially in diabetics leads to increased incidence of heart attacks and strokes as well as peripheral vascular events. In this work, we propose a new multi...

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Veröffentlicht in:	Journal of the Royal Society interface 2021-02, Vol.18 (175), p.20200834-20200834, Article rsif.2020.0834
Hauptverfasser:	Yazdani, Alireza, Deng, Yixiang, Li, He, Javadi, Elahe, Li, Zhen, Jamali, Safa, Lin, Chensen, Humphrey, Jay D, Mantzoros, Christos S, Em Karniadakis, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesives Blood Coagulation Blood Platelets Diabetes Mellitus Humans Life Sciences–Engineering interface Thrombosis
Online-Zugang:	Volltext
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