Cross-Species Physiological Assessment of Brain Estrogen Receptor Expression Using 18F-FES and 18F-4FMFES PET Imaging

Purpose A retrospective analysis was performed of preclinical and clinical data acquired during the evaluation of the estrogen receptor (ER) PET tracer 4-fluoro-11β-methoxy-16α-[ 18 F]-fluoroestradiol (4FMFES) and its comparison with 16α-[ 18 F]-fluoroestradiol (FES) in mice, rats, and humans with a...

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Veröffentlicht in:	Molecular imaging and biology 2020-10, Vol.22 (5), p.1403-1413
Hauptverfasser:	Paquette, Michel, Phoenix, Serge, Lavallée, Éric, Rousseau, Jacques A., Guérin, Brigitte, Turcotte, Éric E., Lecomte, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Autoradiography Brain Breast cancer Cognitive ability Computed tomography Computer vision Data acquisition Estrogen receptors Estrogens Field of view Fluorine isotopes High resolution Image processing Image resolution Imaging Localization Medical imaging Medicine Medicine & Public Health Mice Neuroimaging Ovariectomy Pituitary (anterior) Positron emission Positron emission tomography Preoptic area Radiology Receptors Research Article Rodents Spatial discrimination Spatial resolution Species Tomography Visualization
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