Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo

Extracellular vesicles (EVs) are naturally released, cell-derived vesicles that mediate intracellular communication, in part, by transferring genetic information and, thus, have the potential to be modified for use as a therapeutic gene or drug delivery vehicle. Advances in EV engineering suggest th...

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Veröffentlicht in:	Nanotheranostics (Sydney, NSW) NSW), 2021, Vol.5 (4), p.378-390
Hauptverfasser:	Komuro, Hiroaki, Kawai-Harada, Yuki, Aminova, Shakhlo, Pascual, Nathaniel, Malik, Anshu, Contag, Christopher H, Harada, Masako
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioengineering - methods Contrast Media - chemistry Contrast Media - pharmacokinetics Drug Delivery Systems - methods Extracellular Vesicles Female HEK293 Cells Humans Insulin-Secreting Cells - cytology Insulin-Secreting Cells - metabolism Mice Mice, Inbred BALB C Pancreas - metabolism Plasmids - genetics Research Paper Tissue Distribution
Online-Zugang:	Volltext
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