Physiologically Active Molecules and Functional Properties of Soybeans in Human Health-A Current Perspective
In addition to providing nutrients, food can help prevent and treat certain diseases. In particular, research on soy products has increased dramatically following their emergence as functional foods capable of improving blood circulation and intestinal regulation. In addition to their nutritional va...
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description | In addition to providing nutrients, food can help prevent and treat certain diseases. In particular, research on soy products has increased dramatically following their emergence as functional foods capable of improving blood circulation and intestinal regulation. In addition to their nutritional value, soybeans contain specific phytochemical substances that promote health and are a source of dietary fiber, phospholipids, isoflavones (e.g., genistein and daidzein), phenolic acids, saponins, and phytic acid, while serving as a trypsin inhibitor. These individual substances have demonstrated effectiveness in preventing chronic diseases, such as arteriosclerosis, cardiac diseases, diabetes, and senile dementia, as well as in treating cancer and suppressing osteoporosis. Furthermore, soybean can affect fibrinolytic activity, control blood pressure, and improve lipid metabolism, while eliciting antimutagenic, anticarcinogenic, and antibacterial effects. In this review, rather than to improve on the established studies on the reported nutritional qualities of soybeans, we intend to examine the physiological activities of soybeans that have recently been studied and confirm their potential as a high-functional, well-being food. |
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In particular, research on soy products has increased dramatically following their emergence as functional foods capable of improving blood circulation and intestinal regulation. In addition to their nutritional value, soybeans contain specific phytochemical substances that promote health and are a source of dietary fiber, phospholipids, isoflavones (e.g., genistein and daidzein), phenolic acids, saponins, and phytic acid, while serving as a trypsin inhibitor. These individual substances have demonstrated effectiveness in preventing chronic diseases, such as arteriosclerosis, cardiac diseases, diabetes, and senile dementia, as well as in treating cancer and suppressing osteoporosis. Furthermore, soybean can affect fibrinolytic activity, control blood pressure, and improve lipid metabolism, while eliciting antimutagenic, anticarcinogenic, and antibacterial effects. In this review, rather than to improve on the established studies on the reported nutritional qualities of soybeans, we intend to examine the physiological activities of soybeans that have recently been studied and confirm their potential as a high-functional, well-being food.</description><identifier>ISSN: 1422-0067</identifier><identifier>ISSN: 1661-6596</identifier><identifier>EISSN: 1422-0067</identifier><identifier>DOI: 10.3390/ijms22084054</identifier><identifier>PMID: 33920015</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Antibacterial activity ; Antiinfectives and antibacterials ; Antioxidants ; Arteriosclerosis ; Bacteria ; Biomedical materials ; Blood circulation ; Blood Circulation - drug effects ; Blood pressure ; Blood Pressure - drug effects ; Breast cancer ; Cell division ; Cholesterol ; Coronary artery disease ; Daidzein ; Dementia disorders ; Diabetes ; Diabetes mellitus ; Dietary Fiber ; Estrogens ; Fatty acids ; Fibrin ; Fibrinolytic Agents - chemistry ; Fibrinolytic Agents - therapeutic use ; Flavonoids ; Food cans ; Food products ; Functional foods & nutraceuticals ; Genistein ; Glycine max - chemistry ; Heart diseases ; Humans ; Intestines - drug effects ; Isoflavones ; Isoflavones - chemistry ; Isoflavones - therapeutic use ; Kinases ; Lipid metabolism ; Lipid Metabolism - drug effects ; Lipids ; Menopause ; Metabolism ; Nutrients ; Nutritive value ; Osteoporosis ; Phenolic acids ; Phospholipids ; Phospholipids - chemistry ; Phospholipids - therapeutic use ; Physiology ; Phytic acid ; Phytochemicals ; Prevention ; Prostate ; Proteins ; Review ; Saponins ; Soybeans ; Trypsin ; Trypsin inhibitors ; Well being ; Womens health</subject><ispartof>International journal of molecular sciences, 2021-04, Vol.22 (8), p.4054</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c478t-ae062b1161f9fa0a3fc55475bf9b4cdc5a1259ccecac679772dccec825bf969d3</citedby><cites>FETCH-LOGICAL-c478t-ae062b1161f9fa0a3fc55475bf9b4cdc5a1259ccecac679772dccec825bf969d3</cites><orcidid>0000-0003-2579-2027 ; 0000-0002-6323-0714</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071044/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071044/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33920015$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Il-Sup</creatorcontrib><creatorcontrib>Kim, Cheorl-Ho</creatorcontrib><creatorcontrib>Yang, Woong-Suk</creatorcontrib><title>Physiologically Active Molecules and Functional Properties of Soybeans in Human Health-A Current Perspective</title><title>International journal of molecular sciences</title><addtitle>Int J Mol Sci</addtitle><description>In addition to providing nutrients, food can help prevent and treat certain diseases. In particular, research on soy products has increased dramatically following their emergence as functional foods capable of improving blood circulation and intestinal regulation. In addition to their nutritional value, soybeans contain specific phytochemical substances that promote health and are a source of dietary fiber, phospholipids, isoflavones (e.g., genistein and daidzein), phenolic acids, saponins, and phytic acid, while serving as a trypsin inhibitor. These individual substances have demonstrated effectiveness in preventing chronic diseases, such as arteriosclerosis, cardiac diseases, diabetes, and senile dementia, as well as in treating cancer and suppressing osteoporosis. Furthermore, soybean can affect fibrinolytic activity, control blood pressure, and improve lipid metabolism, while eliciting antimutagenic, anticarcinogenic, and antibacterial effects. In this review, rather than to improve on the established studies on the reported nutritional qualities of soybeans, we intend to examine the physiological activities of soybeans that have recently been studied and confirm their potential as a high-functional, well-being food.</description><subject>Antibacterial activity</subject><subject>Antiinfectives and antibacterials</subject><subject>Antioxidants</subject><subject>Arteriosclerosis</subject><subject>Bacteria</subject><subject>Biomedical materials</subject><subject>Blood circulation</subject><subject>Blood Circulation - drug effects</subject><subject>Blood pressure</subject><subject>Blood Pressure - drug effects</subject><subject>Breast cancer</subject><subject>Cell division</subject><subject>Cholesterol</subject><subject>Coronary artery disease</subject><subject>Daidzein</subject><subject>Dementia disorders</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Dietary Fiber</subject><subject>Estrogens</subject><subject>Fatty acids</subject><subject>Fibrin</subject><subject>Fibrinolytic Agents - chemistry</subject><subject>Fibrinolytic Agents - therapeutic use</subject><subject>Flavonoids</subject><subject>Food cans</subject><subject>Food products</subject><subject>Functional foods & nutraceuticals</subject><subject>Genistein</subject><subject>Glycine max - chemistry</subject><subject>Heart diseases</subject><subject>Humans</subject><subject>Intestines - drug effects</subject><subject>Isoflavones</subject><subject>Isoflavones - chemistry</subject><subject>Isoflavones - therapeutic use</subject><subject>Kinases</subject><subject>Lipid metabolism</subject><subject>Lipid Metabolism - drug effects</subject><subject>Lipids</subject><subject>Menopause</subject><subject>Metabolism</subject><subject>Nutrients</subject><subject>Nutritive value</subject><subject>Osteoporosis</subject><subject>Phenolic acids</subject><subject>Phospholipids</subject><subject>Phospholipids - chemistry</subject><subject>Phospholipids - therapeutic use</subject><subject>Physiology</subject><subject>Phytic acid</subject><subject>Phytochemicals</subject><subject>Prevention</subject><subject>Prostate</subject><subject>Proteins</subject><subject>Review</subject><subject>Saponins</subject><subject>Soybeans</subject><subject>Trypsin</subject><subject>Trypsin inhibitors</subject><subject>Well being</subject><subject>Womens health</subject><issn>1422-0067</issn><issn>1661-6596</issn><issn>1422-0067</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkdFP2zAQxq0JtHZsbzwjS7zwQJjt2HHyglRVdEwCUWnbs-U4F-rKiYudVOp_jwsMFV589t3Pn-7uQ-iUkqs8r8hPu-4iY6TkRPAvaEo5YxkhhTw6uE_QtxjXhLCcieormqSPjBAqpsgtV7tovfOP1mjndnhmBrsFfO8dmNFBxLpv8GLsU9r32uFl8BsIg00V3-I_fleD7iO2Pb4dO51O0G5YZTM8H0OAfsBLCHEDL6rf0XGrXYQfb_EE_Vvc_J3fZncPv37PZ3eZ4bIcMg2kYDWlBW2rVhOdt0YILkXdVjU3jRGapjGMAaNNISspWbN_lGxPFFWTn6DrV93NWHfQmNRG0E5tgu102CmvrfpY6e1KPfqtKomkhPMkcPEmEPzTCHFQnY0GnNM9-DEqJtLCRSXKPKHnn9C1H0Pa1J7ipeR5WchEXb5SJvgYA7TvzVCi9jaqQxsTfnY4wDv837f8GWsrm40</recordid><startdate>20210414</startdate><enddate>20210414</enddate><creator>Kim, Il-Sup</creator><creator>Kim, Cheorl-Ho</creator><creator>Yang, Woong-Suk</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2579-2027</orcidid><orcidid>https://orcid.org/0000-0002-6323-0714</orcidid></search><sort><creationdate>20210414</creationdate><title>Physiologically Active Molecules and Functional Properties of Soybeans in Human Health-A Current Perspective</title><author>Kim, Il-Sup ; Kim, Cheorl-Ho ; Yang, Woong-Suk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-ae062b1161f9fa0a3fc55475bf9b4cdc5a1259ccecac679772dccec825bf969d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antibacterial activity</topic><topic>Antiinfectives and antibacterials</topic><topic>Antioxidants</topic><topic>Arteriosclerosis</topic><topic>Bacteria</topic><topic>Biomedical materials</topic><topic>Blood circulation</topic><topic>Blood Circulation - drug effects</topic><topic>Blood pressure</topic><topic>Blood Pressure - drug effects</topic><topic>Breast cancer</topic><topic>Cell division</topic><topic>Cholesterol</topic><topic>Coronary artery disease</topic><topic>Daidzein</topic><topic>Dementia disorders</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Dietary Fiber</topic><topic>Estrogens</topic><topic>Fatty acids</topic><topic>Fibrin</topic><topic>Fibrinolytic Agents - chemistry</topic><topic>Fibrinolytic Agents - therapeutic use</topic><topic>Flavonoids</topic><topic>Food cans</topic><topic>Food products</topic><topic>Functional foods & nutraceuticals</topic><topic>Genistein</topic><topic>Glycine max - chemistry</topic><topic>Heart diseases</topic><topic>Humans</topic><topic>Intestines - drug effects</topic><topic>Isoflavones</topic><topic>Isoflavones - chemistry</topic><topic>Isoflavones - therapeutic use</topic><topic>Kinases</topic><topic>Lipid metabolism</topic><topic>Lipid Metabolism - drug effects</topic><topic>Lipids</topic><topic>Menopause</topic><topic>Metabolism</topic><topic>Nutrients</topic><topic>Nutritive value</topic><topic>Osteoporosis</topic><topic>Phenolic acids</topic><topic>Phospholipids</topic><topic>Phospholipids - chemistry</topic><topic>Phospholipids - therapeutic use</topic><topic>Physiology</topic><topic>Phytic acid</topic><topic>Phytochemicals</topic><topic>Prevention</topic><topic>Prostate</topic><topic>Proteins</topic><topic>Review</topic><topic>Saponins</topic><topic>Soybeans</topic><topic>Trypsin</topic><topic>Trypsin inhibitors</topic><topic>Well being</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Il-Sup</creatorcontrib><creatorcontrib>Kim, Cheorl-Ho</creatorcontrib><creatorcontrib>Yang, Woong-Suk</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of molecular sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Il-Sup</au><au>Kim, Cheorl-Ho</au><au>Yang, Woong-Suk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Physiologically Active Molecules and Functional Properties of Soybeans in Human Health-A Current Perspective</atitle><jtitle>International journal of molecular sciences</jtitle><addtitle>Int J Mol Sci</addtitle><date>2021-04-14</date><risdate>2021</risdate><volume>22</volume><issue>8</issue><spage>4054</spage><pages>4054-</pages><issn>1422-0067</issn><issn>1661-6596</issn><eissn>1422-0067</eissn><abstract>In addition to providing nutrients, food can help prevent and treat certain diseases. In particular, research on soy products has increased dramatically following their emergence as functional foods capable of improving blood circulation and intestinal regulation. In addition to their nutritional value, soybeans contain specific phytochemical substances that promote health and are a source of dietary fiber, phospholipids, isoflavones (e.g., genistein and daidzein), phenolic acids, saponins, and phytic acid, while serving as a trypsin inhibitor. These individual substances have demonstrated effectiveness in preventing chronic diseases, such as arteriosclerosis, cardiac diseases, diabetes, and senile dementia, as well as in treating cancer and suppressing osteoporosis. Furthermore, soybean can affect fibrinolytic activity, control blood pressure, and improve lipid metabolism, while eliciting antimutagenic, anticarcinogenic, and antibacterial effects. In this review, rather than to improve on the established studies on the reported nutritional qualities of soybeans, we intend to examine the physiological activities of soybeans that have recently been studied and confirm their potential as a high-functional, well-being food.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33920015</pmid><doi>10.3390/ijms22084054</doi><orcidid>https://orcid.org/0000-0003-2579-2027</orcidid><orcidid>https://orcid.org/0000-0002-6323-0714</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Antibacterial activity Antiinfectives and antibacterials Antioxidants Arteriosclerosis Bacteria Biomedical materials Blood circulation Blood Circulation - drug effects Blood pressure Blood Pressure - drug effects Breast cancer Cell division Cholesterol Coronary artery disease Daidzein Dementia disorders Diabetes Diabetes mellitus Dietary Fiber Estrogens Fatty acids Fibrin Fibrinolytic Agents - chemistry Fibrinolytic Agents - therapeutic use Flavonoids Food cans Food products Functional foods & nutraceuticals Genistein Glycine max - chemistry Heart diseases Humans Intestines - drug effects Isoflavones Isoflavones - chemistry Isoflavones - therapeutic use Kinases Lipid metabolism Lipid Metabolism - drug effects Lipids Menopause Metabolism Nutrients Nutritive value Osteoporosis Phenolic acids Phospholipids Phospholipids - chemistry Phospholipids - therapeutic use Physiology Phytic acid Phytochemicals Prevention Prostate Proteins Review Saponins Soybeans Trypsin Trypsin inhibitors Well being Womens health |
title | Physiologically Active Molecules and Functional Properties of Soybeans in Human Health-A Current Perspective |
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