Effect of Central Corticotropin-Releasing Factor on Hepatic Lipid Metabolism and Inflammation-Related Gene Expression in Rats

Corticotropin-releasing factor (CRF) in the brain acts on physiological and pathophysiological modulation of the hepatobiliary system. Central CRF administration aggravates experimental acute liver injury by decreasing hepatic blood flow. Conversely, minimal evidence is available regarding the effec...

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Veröffentlicht in:	International journal of molecular sciences 2021-04, Vol.22 (8), p.3940
Hauptverfasser:	Nakade, Yukiomi, Kitano, Rena, Yamauchi, Taeko, Kimoto, Satoshi, Sakamoto, Kazumasa, Inoue, Tadahisa, Kobayashi, Yuji, Ohashi, Tomohiko, Sumida, Yoshio, Ito, Kiyoaki, Yoneda, Masashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atropine Blood flow Corticotropin-releasing hormone Corticotropin-Releasing Hormone - pharmacology Gene expression Gene Expression Regulation - drug effects Guanethidine Hepatitis - metabolism Hepatitis - pathology Hypothalamus Inflammation Inflammation - metabolism Inflammation - pathology Interleukin 1 Lipid metabolism Lipid Metabolism - drug effects Lipids Lipogenesis Liver Liver - metabolism Liver - pathology Male Metabolism Motility Nervous system Neuropeptides Norepinephrine Phenols Physiological effects Physiology Rats Rats, Long-Evans Regulatory sequences Sympathetic nervous system Tumor necrosis factor-α vagotomy
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