Advances in anti-BRAF therapies for lung cancer

Summary Non-small cell lung cancer (NSCLC) is one of the most frequent causes of mortality in the western world. v-raf murine sarcoma viral oncogene homolog B (BRAF) is a member of the Raf kinase family and plays a critical role in cellular growth, proliferation, and differentiation through the mito...

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Veröffentlicht in:	Investigational new drugs 2021-06, Vol.39 (3), p.879-890
Hauptverfasser:	Roviello, Giandomenico, D’Angelo, Alberto, Sirico, Marianna, Pittacolo, Matteo, Conter, Felipe Umpierre, Sobhani, Navid
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Clinical trials Drug Resistance, Neoplasm - genetics Homology Humans Kinases Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - genetics MAP kinase Medicine Medicine & Public Health Melanoma Metastases Mutation Non-small cell lung carcinoma Oncology Pharmacology/Toxicology Protein kinase Protein Kinase Inhibitors - therapeutic use Proto-Oncogene Proteins B-raf - antagonists & inhibitors Proto-Oncogene Proteins B-raf - genetics Raf protein Review Sarcoma Small cell lung carcinoma
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