Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique
: To find an objective diagnostic tool for the superficial veins in legs. : This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases underwent a QFlow scan and were classified into the reflux and non-reflux gro...
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| Veröffentlicht in: | Journal of personalized medicine 2021-03, Vol.11 (4), p.242 |
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| container_title | Journal of personalized medicine |
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| creator | Tseng, Yuan-Hsi Chen, Chien-Wei Wong, Min Yi Yang, Teng-Yao Lin, Bor-Shyh Ting, Hua Huang, Yao-Kuang |
| description | : To find an objective diagnostic tool for the superficial veins in legs.
: This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases underwent a QFlow scan and were classified into the reflux and non-reflux groups according to the status of the great saphenous veins.
: The QFlow, namely stroke volume (SV), forward flow volume (FFV), mean flux (MF), stroke distance (SD), and mean velocity (MV) measured in the external iliac, femoral, popliteal, and great saphenous vein (GSV). The SV, FFV, SD, MF, SD, and MV in the GSV (morbid/non-morbid limbs) demonstrated a favorable ability to discriminate reflux from non-reflux in the ROC curve. The SD in the GSV and GSV/PV ratio (
= 0.049 and 0.047/cutoff = 86 and 117.1) and the MV in the EIV/FV ratio, GSV, and GSV/PV ratio (
= 0.035, 0.034, and 0.025/cutoff = 100.9, 86.1, and 122.9) exhibited the ability to discriminate between reflux and non-reflux group. The SD, MV, and FFV have better ability to discriminate a reflux from non-reflux group than the SV and MF.
: QFlow may be used to verify the reflux of superficial veins in the legs. An increasing GSV/PV ratio is a hallmark of reflux of superficial veins in the legs. |
| doi_str_mv | 10.3390/jpm11040242 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8066982</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2508566123</sourcerecordid><originalsourceid>FETCH-LOGICAL-c409t-1f6a092af1e36aadaebf29e88f6ff0148362c5bd76910aa078ba61891bf7b76a3</originalsourceid><addsrcrecordid>eNpdkUFv1DAQhS1ERavSE3dkiQsSCoztxHEuSGihLdIWRClcLSc73vUqsbd20rL_vi5dqi2-2CN_8_RmHiGvGLwXooEP683AGJTAS_6MHHGoq6IsuXy-9z4kJymtIR9VcS7hBTkUQjGoAI7I9rNLXXSD82Z0fkkv0fbTH2pjGOi34ItdnSk0CRMNlv6cNhit65zp6W90PlHn6RyXibbb3HOD_d_OWfBjNGmkF5f01o0r-uO0D7f0CruVd9cTviQH1vQJT3b3Mfl1-uVqdl7Mv599nX2aF10JzVgwKw003FiGQhqzMNha3qBSVloLrFRC8q5qF7VsGBgDtWqNZKphra3bWhpxTD4-6G6mdsBFh_e2er3JQ5u41cE4_fTHu5VehhutQMpG8SzwdicQQ_adRj3knWHfG49hSppXebFSMi4y-uY_dB2m6PN4mRKMlQ1UZabePVBdDClFtI9mGOj7VPVeqpl-ve__kf2XobgDCFeeUA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2531149054</pqid></control><display><type>article</type><title>Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique</title><source>Open Access: PubMed Central</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>Free E-Journal (出版社公開部分のみ）</source><source>PubMed Central Open Access</source><creator>Tseng, Yuan-Hsi ; Chen, Chien-Wei ; Wong, Min Yi ; Yang, Teng-Yao ; Lin, Bor-Shyh ; Ting, Hua ; Huang, Yao-Kuang</creator><creatorcontrib>Tseng, Yuan-Hsi ; Chen, Chien-Wei ; Wong, Min Yi ; Yang, Teng-Yao ; Lin, Bor-Shyh ; Ting, Hua ; Huang, Yao-Kuang</creatorcontrib><description>: To find an objective diagnostic tool for the superficial veins in legs.
: This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases underwent a QFlow scan and were classified into the reflux and non-reflux groups according to the status of the great saphenous veins.
: The QFlow, namely stroke volume (SV), forward flow volume (FFV), mean flux (MF), stroke distance (SD), and mean velocity (MV) measured in the external iliac, femoral, popliteal, and great saphenous vein (GSV). The SV, FFV, SD, MF, SD, and MV in the GSV (morbid/non-morbid limbs) demonstrated a favorable ability to discriminate reflux from non-reflux in the ROC curve. The SD in the GSV and GSV/PV ratio (
= 0.049 and 0.047/cutoff = 86 and 117.1) and the MV in the EIV/FV ratio, GSV, and GSV/PV ratio (
= 0.035, 0.034, and 0.025/cutoff = 100.9, 86.1, and 122.9) exhibited the ability to discriminate between reflux and non-reflux group. The SD, MV, and FFV have better ability to discriminate a reflux from non-reflux group than the SV and MF.
: QFlow may be used to verify the reflux of superficial veins in the legs. An increasing GSV/PV ratio is a hallmark of reflux of superficial veins in the legs.</description><identifier>ISSN: 2075-4426</identifier><identifier>EISSN: 2075-4426</identifier><identifier>DOI: 10.3390/jpm11040242</identifier><identifier>PMID: 33810500</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Contrast agents ; Datasets ; Discrimination ; Drug use ; Flow velocity ; Leg ; Legs ; Magnetic resonance imaging ; Medical imaging ; Precision medicine ; TRANCE protein ; Ulcers ; Ultrasonic imaging ; Veins & arteries</subject><ispartof>Journal of personalized medicine, 2021-03, Vol.11 (4), p.242</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-1f6a092af1e36aadaebf29e88f6ff0148362c5bd76910aa078ba61891bf7b76a3</citedby><cites>FETCH-LOGICAL-c409t-1f6a092af1e36aadaebf29e88f6ff0148362c5bd76910aa078ba61891bf7b76a3</cites><orcidid>0000-0002-8653-2571</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066982/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066982/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33810500$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tseng, Yuan-Hsi</creatorcontrib><creatorcontrib>Chen, Chien-Wei</creatorcontrib><creatorcontrib>Wong, Min Yi</creatorcontrib><creatorcontrib>Yang, Teng-Yao</creatorcontrib><creatorcontrib>Lin, Bor-Shyh</creatorcontrib><creatorcontrib>Ting, Hua</creatorcontrib><creatorcontrib>Huang, Yao-Kuang</creatorcontrib><title>Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique</title><title>Journal of personalized medicine</title><addtitle>J Pers Med</addtitle><description>: To find an objective diagnostic tool for the superficial veins in legs.
: This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases underwent a QFlow scan and were classified into the reflux and non-reflux groups according to the status of the great saphenous veins.
: The QFlow, namely stroke volume (SV), forward flow volume (FFV), mean flux (MF), stroke distance (SD), and mean velocity (MV) measured in the external iliac, femoral, popliteal, and great saphenous vein (GSV). The SV, FFV, SD, MF, SD, and MV in the GSV (morbid/non-morbid limbs) demonstrated a favorable ability to discriminate reflux from non-reflux in the ROC curve. The SD in the GSV and GSV/PV ratio (
= 0.049 and 0.047/cutoff = 86 and 117.1) and the MV in the EIV/FV ratio, GSV, and GSV/PV ratio (
= 0.035, 0.034, and 0.025/cutoff = 100.9, 86.1, and 122.9) exhibited the ability to discriminate between reflux and non-reflux group. The SD, MV, and FFV have better ability to discriminate a reflux from non-reflux group than the SV and MF.
: QFlow may be used to verify the reflux of superficial veins in the legs. An increasing GSV/PV ratio is a hallmark of reflux of superficial veins in the legs.</description><subject>Contrast agents</subject><subject>Datasets</subject><subject>Discrimination</subject><subject>Drug use</subject><subject>Flow velocity</subject><subject>Leg</subject><subject>Legs</subject><subject>Magnetic resonance imaging</subject><subject>Medical imaging</subject><subject>Precision medicine</subject><subject>TRANCE protein</subject><subject>Ulcers</subject><subject>Ultrasonic imaging</subject><subject>Veins & arteries</subject><issn>2075-4426</issn><issn>2075-4426</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkUFv1DAQhS1ERavSE3dkiQsSCoztxHEuSGihLdIWRClcLSc73vUqsbd20rL_vi5dqi2-2CN_8_RmHiGvGLwXooEP683AGJTAS_6MHHGoq6IsuXy-9z4kJymtIR9VcS7hBTkUQjGoAI7I9rNLXXSD82Z0fkkv0fbTH2pjGOi34ItdnSk0CRMNlv6cNhit65zp6W90PlHn6RyXibbb3HOD_d_OWfBjNGmkF5f01o0r-uO0D7f0CruVd9cTviQH1vQJT3b3Mfl1-uVqdl7Mv599nX2aF10JzVgwKw003FiGQhqzMNha3qBSVloLrFRC8q5qF7VsGBgDtWqNZKphra3bWhpxTD4-6G6mdsBFh_e2er3JQ5u41cE4_fTHu5VehhutQMpG8SzwdicQQ_adRj3knWHfG49hSppXebFSMi4y-uY_dB2m6PN4mRKMlQ1UZabePVBdDClFtI9mGOj7VPVeqpl-ve__kf2XobgDCFeeUA</recordid><startdate>20210326</startdate><enddate>20210326</enddate><creator>Tseng, Yuan-Hsi</creator><creator>Chen, Chien-Wei</creator><creator>Wong, Min Yi</creator><creator>Yang, Teng-Yao</creator><creator>Lin, Bor-Shyh</creator><creator>Ting, Hua</creator><creator>Huang, Yao-Kuang</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8653-2571</orcidid></search><sort><creationdate>20210326</creationdate><title>Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique</title><author>Tseng, Yuan-Hsi ; Chen, Chien-Wei ; Wong, Min Yi ; Yang, Teng-Yao ; Lin, Bor-Shyh ; Ting, Hua ; Huang, Yao-Kuang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-1f6a092af1e36aadaebf29e88f6ff0148362c5bd76910aa078ba61891bf7b76a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Contrast agents</topic><topic>Datasets</topic><topic>Discrimination</topic><topic>Drug use</topic><topic>Flow velocity</topic><topic>Leg</topic><topic>Legs</topic><topic>Magnetic resonance imaging</topic><topic>Medical imaging</topic><topic>Precision medicine</topic><topic>TRANCE protein</topic><topic>Ulcers</topic><topic>Ultrasonic imaging</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tseng, Yuan-Hsi</creatorcontrib><creatorcontrib>Chen, Chien-Wei</creatorcontrib><creatorcontrib>Wong, Min Yi</creatorcontrib><creatorcontrib>Yang, Teng-Yao</creatorcontrib><creatorcontrib>Lin, Bor-Shyh</creatorcontrib><creatorcontrib>Ting, Hua</creatorcontrib><creatorcontrib>Huang, Yao-Kuang</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Biological Sciences</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of personalized medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tseng, Yuan-Hsi</au><au>Chen, Chien-Wei</au><au>Wong, Min Yi</au><au>Yang, Teng-Yao</au><au>Lin, Bor-Shyh</au><au>Ting, Hua</au><au>Huang, Yao-Kuang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique</atitle><jtitle>Journal of personalized medicine</jtitle><addtitle>J Pers Med</addtitle><date>2021-03-26</date><risdate>2021</risdate><volume>11</volume><issue>4</issue><spage>242</spage><pages>242-</pages><issn>2075-4426</issn><eissn>2075-4426</eissn><abstract>: To find an objective diagnostic tool for the superficial veins in legs.
: This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases underwent a QFlow scan and were classified into the reflux and non-reflux groups according to the status of the great saphenous veins.
: The QFlow, namely stroke volume (SV), forward flow volume (FFV), mean flux (MF), stroke distance (SD), and mean velocity (MV) measured in the external iliac, femoral, popliteal, and great saphenous vein (GSV). The SV, FFV, SD, MF, SD, and MV in the GSV (morbid/non-morbid limbs) demonstrated a favorable ability to discriminate reflux from non-reflux in the ROC curve. The SD in the GSV and GSV/PV ratio (
= 0.049 and 0.047/cutoff = 86 and 117.1) and the MV in the EIV/FV ratio, GSV, and GSV/PV ratio (
= 0.035, 0.034, and 0.025/cutoff = 100.9, 86.1, and 122.9) exhibited the ability to discriminate between reflux and non-reflux group. The SD, MV, and FFV have better ability to discriminate a reflux from non-reflux group than the SV and MF.
: QFlow may be used to verify the reflux of superficial veins in the legs. An increasing GSV/PV ratio is a hallmark of reflux of superficial veins in the legs.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33810500</pmid><doi>10.3390/jpm11040242</doi><orcidid>https://orcid.org/0000-0002-8653-2571</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Open Access: PubMed Central; MDPI - Multidisciplinary Digital Publishing Institute; Free E-Journal (出版社公開部分のみ）; PubMed Central Open Access |
| subjects | Contrast agents Datasets Discrimination Drug use Flow velocity Leg Legs Magnetic resonance imaging Medical imaging Precision medicine TRANCE protein Ulcers Ultrasonic imaging Veins & arteries |
| title | Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique |
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