Natural history of monoclonal B-cell lymphocytosis among relatives in CLL families

Chronic lymphocytic lymphoma (CLL) has one of the highest familial risks among cancers. Monoclonal B-cell lymphocytosis (MBL), the precursor to CLL, has a higher prevalence (13%-18%) in families with 2 or more members with CLL compared with the general population (5%-12%). Although, the rate of prog...

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Veröffentlicht in:	Blood 2021-04, Vol.137 (15), p.2046-2056
Hauptverfasser:	Slager, Susan L., Lanasa, Mark C., Marti, Gerald E., Achenbach, Sara J., Camp, Nicola J., Abbasi, Fatima, Kay, Neil E., Vachon, Celine M., Cerhan, James R., Johnston, James B., Call, Timothy G., Rabe, Kari G., Kleinstern, Geffen, Boddicker, Nicholas J., Norman, Aaron D., Parikh, Sameer A., Leis, Jose F., Banerji, Versha, Brander, Danielle M., Glenn, Martha, Ferrajoli, Alessandra, Curtin, Karen, Braggio, Esteban, Shanafelt, Tait D., McMaster, Mary L., Weinberg, J. Brice, Hanson, Curtis A., Caporaso, Neil E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over B-Lymphocytes - pathology CME Disease Progression Female Humans Incidence Kaplan-Meier Estimate Leukemia, Lymphocytic, Chronic, B-Cell - etiology Lymphocytosis - complications Lymphocytosis - diagnosis Lymphocytosis - etiology Lymphocytosis - pathology Lymphoid Neoplasia Male Middle Aged Pedigree
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