Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions

Embryo morphogenesis is impacted by dynamic changes in tissue material properties, which have been proposed to occur via processes akin to phase transitions (PTs). Here, we show that rigidity percolation provides a simple and robust theoretical framework to predict material/structural PTs of embryon...

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Veröffentlicht in:	Cell 2021-04, Vol.184 (7), p.1914-1928.e19
Hauptverfasser:	Petridou, Nicoletta I., Corominas-Murtra, Bernat, Heisenberg, Carl-Philipp, Hannezo, Edouard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blastoderm - cytology Blastoderm - physiology Cadherins - antagonists & inhibitors Cadherins - genetics Cadherins - metabolism Cell Adhesion cell mechanics cell-contact network embryo morphogenesis Embryo, Nonmammalian - cytology Embryo, Nonmammalian - physiology Embryonic Development Morpholinos - metabolism phase transition Rheology rigidity percolation Theory tissue rheology Viscosity Zebrafish - growth & development
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