Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia
An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstructi...
Gespeichert in:
Veröffentlicht in: | BMJ case reports 2021-04, Vol.14 (4), p.e240786 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | 4 |
container_start_page | e240786 |
container_title | BMJ case reports |
container_volume | 14 |
creator | Ferrel, Benjamin Franko, Jan Tee, May C |
description | An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstruction, resulting in successful removal of the tumour with negative margins. Medical and surgical management of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is discussed. |
doi_str_mv | 10.1136/bcr-2020-240786 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8054046</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2514595766</sourcerecordid><originalsourceid>FETCH-LOGICAL-c393t-ded707cd1b51b159b5bb52c64a807a461d1ad5062a2144f4badbb7b04319ecc83</originalsourceid><addsrcrecordid>eNpVkd9LwzAQx4MoTuaefZM--lJNmqRpXwQZ_oKBIAr6FC7pbau0TU1aYf-9LZtj3ssd3Pe-d8eHkAtGrxnj6Y2xPk5oQuNEUJWlR-SMKalildOP44N6QmYhfNEhOBOZ4KdkwnkmsyznZ-TzFTxGFgJGbhm10FiP0JU2arD3DpvCWV82GHV97XoftR4DNl3ZrCIIg9xDg66tIIwj602L3kJlAesSzsnJEqqAs12ekveH-7f5U7x4eXye3y1iy3PexQUWiipbMCOZYTI30hiZ2FRARhWIlBUMCknTBBImxFIYKIxRhgrOcrQ241Nyu_Vte1NjYYfzPFS69WUNfqMdlPp_pynXeuV-dEaloCIdDK52Bt599xg6XZfBYlWNv_VBJ5IJmUuVjtKbrdR6F4LH5X4No3pkogcmemSit0yGicvD6_b6PwL8F9mgiy8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2514595766</pqid></control><display><type>article</type><title>Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia</title><source>MEDLINE</source><source>PubMed Central</source><source>EZB Electronic Journals Library</source><creator>Ferrel, Benjamin ; Franko, Jan ; Tee, May C</creator><creatorcontrib>Ferrel, Benjamin ; Franko, Jan ; Tee, May C</creatorcontrib><description>An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstruction, resulting in successful removal of the tumour with negative margins. Medical and surgical management of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is discussed.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-240786</identifier><identifier>PMID: 33858893</identifier><language>eng</language><publisher>England: BMJ Publishing Group</publisher><subject>Aged ; Case Report ; Female ; Humans ; Hypercalcemia - etiology ; Pancreatic Neoplasms - complications ; Pancreatic Neoplasms - diagnosis ; Parathyroid Hormone-Related Protein</subject><ispartof>BMJ case reports, 2021-04, Vol.14 (4), p.e240786</ispartof><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-ded707cd1b51b159b5bb52c64a807a461d1ad5062a2144f4badbb7b04319ecc83</citedby><cites>FETCH-LOGICAL-c393t-ded707cd1b51b159b5bb52c64a807a461d1ad5062a2144f4badbb7b04319ecc83</cites><orcidid>0000-0002-9968-5454</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054046/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054046/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33858893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ferrel, Benjamin</creatorcontrib><creatorcontrib>Franko, Jan</creatorcontrib><creatorcontrib>Tee, May C</creatorcontrib><title>Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstruction, resulting in successful removal of the tumour with negative margins. Medical and surgical management of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is discussed.</description><subject>Aged</subject><subject>Case Report</subject><subject>Female</subject><subject>Humans</subject><subject>Hypercalcemia - etiology</subject><subject>Pancreatic Neoplasms - complications</subject><subject>Pancreatic Neoplasms - diagnosis</subject><subject>Parathyroid Hormone-Related Protein</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkd9LwzAQx4MoTuaefZM--lJNmqRpXwQZ_oKBIAr6FC7pbau0TU1aYf-9LZtj3ssd3Pe-d8eHkAtGrxnj6Y2xPk5oQuNEUJWlR-SMKalildOP44N6QmYhfNEhOBOZ4KdkwnkmsyznZ-TzFTxGFgJGbhm10FiP0JU2arD3DpvCWV82GHV97XoftR4DNl3ZrCIIg9xDg66tIIwj602L3kJlAesSzsnJEqqAs12ekveH-7f5U7x4eXye3y1iy3PexQUWiipbMCOZYTI30hiZ2FRARhWIlBUMCknTBBImxFIYKIxRhgrOcrQ241Nyu_Vte1NjYYfzPFS69WUNfqMdlPp_pynXeuV-dEaloCIdDK52Bt599xg6XZfBYlWNv_VBJ5IJmUuVjtKbrdR6F4LH5X4No3pkogcmemSit0yGicvD6_b6PwL8F9mgiy8</recordid><startdate>20210415</startdate><enddate>20210415</enddate><creator>Ferrel, Benjamin</creator><creator>Franko, Jan</creator><creator>Tee, May C</creator><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9968-5454</orcidid></search><sort><creationdate>20210415</creationdate><title>Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia</title><author>Ferrel, Benjamin ; Franko, Jan ; Tee, May C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-ded707cd1b51b159b5bb52c64a807a461d1ad5062a2144f4badbb7b04319ecc83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aged</topic><topic>Case Report</topic><topic>Female</topic><topic>Humans</topic><topic>Hypercalcemia - etiology</topic><topic>Pancreatic Neoplasms - complications</topic><topic>Pancreatic Neoplasms - diagnosis</topic><topic>Parathyroid Hormone-Related Protein</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ferrel, Benjamin</creatorcontrib><creatorcontrib>Franko, Jan</creatorcontrib><creatorcontrib>Tee, May C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ferrel, Benjamin</au><au>Franko, Jan</au><au>Tee, May C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2021-04-15</date><risdate>2021</risdate><volume>14</volume><issue>4</issue><spage>e240786</spage><pages>e240786-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstruction, resulting in successful removal of the tumour with negative margins. Medical and surgical management of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is discussed.</abstract><cop>England</cop><pub>BMJ Publishing Group</pub><pmid>33858893</pmid><doi>10.1136/bcr-2020-240786</doi><orcidid>https://orcid.org/0000-0002-9968-5454</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1757-790X |
ispartof | BMJ case reports, 2021-04, Vol.14 (4), p.e240786 |
issn | 1757-790X 1757-790X |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8054046 |
source | MEDLINE; PubMed Central; EZB Electronic Journals Library |
subjects | Aged Case Report Female Humans Hypercalcemia - etiology Pancreatic Neoplasms - complications Pancreatic Neoplasms - diagnosis Parathyroid Hormone-Related Protein |
title | Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T16%3A41%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rare%20case%20of%20pancreatic%20neuroendocrine%20tumour%20presenting%20as%20paraneoplastic%20hypercalcaemia&rft.jtitle=BMJ%20case%20reports&rft.au=Ferrel,%20Benjamin&rft.date=2021-04-15&rft.volume=14&rft.issue=4&rft.spage=e240786&rft.pages=e240786-&rft.issn=1757-790X&rft.eissn=1757-790X&rft_id=info:doi/10.1136/bcr-2020-240786&rft_dat=%3Cproquest_pubme%3E2514595766%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2514595766&rft_id=info:pmid/33858893&rfr_iscdi=true |