A uro-protective agent with restorative actions on urethral and striated muscle morphology

Purpose Aging increases oxidative stress, which can have delirious effects on smooth and striated muscle resulting in bladder dysfunction. Consequently, in women aged over 60 years, urinary incontinence (UI) is a prevalent health problem. Despite the prevalence and consequences, UI continues to be u...

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Veröffentlicht in:	World journal of urology 2021-07, Vol.39 (7), p.2685-2690
Hauptverfasser:	Birder, Lori A., Wolf-Johnston, Amanda, Wein, Alan J., Grove-Sullivan, Mara, Stoltz, Donna, Watkins, Simon, Newman, Diane, Dmochowski, Roger R., Jackson, Edwin K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Degeneration Electron microscopy Female Guanine - analogs & derivatives Guanine - pharmacology Guanine - therapeutic use Immunoblotting Medicine Medicine & Public Health Mitochondria Morphology Muscle, Striated - drug effects Muscle, Striated - pathology Nephrology Oncology Original Article Oxidative stress Phosphorylase Placebos Poly(ADP-ribose) polymerase Polynucleotide phosphorylase Random Allocation Rats Rats, Inbred F344 Skeletal muscle Sphincter Urethra Urethra - drug effects Urethra - pathology Urinary incontinence Urinary tract Urogenital system Urology
Online-Zugang:	Volltext
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