ΔNp63 is a pioneer factor that binds inaccessible chromatin and elicits chromatin remodeling

ΔNp63 is a master transcriptional regulator playing critical roles in epidermal development and other cellular processes. Recent studies suggest that ΔNp63 functions as a pioneer factor that can target its binding sites within inaccessible chromatin and induce chromatin remodeling. In order to exami...

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Veröffentlicht in:	Epigenetics & chromatin 2021-04, Vol.14 (1), p.20-20, Article 20
Hauptverfasser:	Yu, Xinyang, Singh, Prashant K, Tabrejee, Shamira, Sinha, Satrajit, Buck, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Antibodies Binding Sites Cell lines Chromatin Chromatin Assembly and Disassembly Chromatin modification Chromatin remodeling Deoxyribonucleic acid DNA Experiments Genes Genomes Histones Histones - metabolism Morphogenesis Nucleosome Nucleosomes P63 Pioneer factor Transcription
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