A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?

COVID-19 has rarely been associated with immune-mediated phenomena such as autoimmune haemolytic anaemia (AIHA). Both cold hemolysis with cold agglutinin detection and warm haemolysis have been described with variable prognoses. Current treatment regimens are based on experience with other case seri...

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Veröffentlicht in:SN comprehensive clinical medicine 2021, Vol.3 (6), p.1420-1423
Hauptverfasser: Ramos-Ruperto, L., García-Pérez, Eduardo, Hernández-Maraver, D., Kerguelén-Fuentes, A., Viejo-Llorente, A., Robles-Marhuenda, Á., Busca-Arenzana, C.
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container_end_page 1423
container_issue 6
container_start_page 1420
container_title SN comprehensive clinical medicine
container_volume 3
creator Ramos-Ruperto, L.
García-Pérez, Eduardo
Hernández-Maraver, D.
Kerguelén-Fuentes, A.
Viejo-Llorente, A.
Robles-Marhuenda, Á.
Busca-Arenzana, C.
description COVID-19 has rarely been associated with immune-mediated phenomena such as autoimmune haemolytic anaemia (AIHA). Both cold hemolysis with cold agglutinin detection and warm haemolysis have been described with variable prognoses. Current treatment regimens are based on experience with other case series and case reports, which still represent a clinical challenge. Corticosteroids, red cell transfusions and rituximab have been successfully employed. We present 3 cases of AIHA in the context of COVID-19 disease, the first case successfully treated with plasma exchange and long-term follow-up of the 3 cases showing complete remission of anaemia.
doi_str_mv 10.1007/s42399-021-00884-6
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subjects Covid-19
Medicine
Medicine & Public Health
Topical Collection on COVID-19
title A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
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