Poison exons in neurodevelopment and disease

Poison exons are naturally occurring, highly conserved alternative exons that contain a premature termination codon. Inclusion of a poison exon in a transcript targets the transcript for nonsense mediated decay, decreasing the amount of protein produced. Poison exons are proposed to play an importan...

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Veröffentlicht in:	Current opinion in genetics & development 2020-12, Vol.65, p.98-102
Hauptverfasser:	Carvill, Gemma L, Mefford, Heather C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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