Brain metabolic changes across King’s stages in amyotrophic lateral sclerosis: a 18F-2-fluoro-2-deoxy-d-glucose-positron emission tomography study

Purpose To assess the brain metabolic correlates of the different regional extent of ALS, evaluated with the King’s staging system, using brain 18 F-2-fluoro-2-deoxy- d -glucose-PET ( 18 F-FDG-PET). Methods Three hundred ninety ALS cases with King’s stages 1, 2, and 3 ( n = 390), i.e., involvement...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2021-04, Vol.48 (4), p.1124-1133
Hauptverfasser:	Canosa, Antonio, Calvo, Andrea, Moglia, Cristina, Manera, Umberto, Vasta, Rosario, Di Pede, Francesca, Cabras, Sara, Nardo, Davide, Arena, Vincenzo, Grassano, Maurizio, D’Ovidio, Fabrizio, Van Laere, Koen, Van Damme, Philip, Pagani, Marco, Chiò, Adriano
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Brain Cardiology Cortex (motor) Emission analysis Factorial design Fluorine isotopes Frontal gyrus Glucose Hypometabolism Hypotheses Imaging Medicine Medicine & Public Health Metabolism Neurodegeneration Neurology Nuclear Medicine Oncology Original Original Article Orthopedics Positron emission Positron emission tomography Radiology Tomography
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