Salting the Soil: Targeting the Microenvironment of Brain Metastases

Paget's "seed and soil" hypothesis of metastatic spread has acted as a foundation of the field for over a century, with continued evolution as mechanisms of the process have been elucidated. The central nervous system (CNS) presents a unique soil through this lens, relatively isolated...

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Veröffentlicht in:	Molecular cancer therapeutics 2021-03, Vol.20 (3), p.455-466
Hauptverfasser:	Srinivasan, Ethan S., Tan, Aaron C., Anders, Carey K., Pendergast, Ann Marie, Sipkins, Dorothy A., Ashley, David M., Fecci, Peter E., Khasraw, Mustafa
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Neoplasms - pathology Humans Life Sciences & Biomedicine Neoplasm Metastasis Oncology Science & Technology Tumor Microenvironment
Online-Zugang:	Volltext
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