A limited role of NKCC1 in telencephalic glutamatergic neurons for developing hippocampal network dynamics and behavior

NKCC1 is the primary transporter mediating chloride uptake in immature principal neurons, but its role in the development of in vivo network dynamics and cognitive abilities remains unknown. Here, we address the function of NKCC1 in developing mice using electrophysiological, optical, and behavioral...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2021-04, Vol.118 (14)
Hauptverfasser: Graf, Jürgen, Zhang, Chuanqiang, Marguet, Stephan Lawrence, Herrmann, Tanja, Flossmann, Tom, Hinsch, Robin, Rahmati, Vahid, Guenther, Madlen, Frahm, Christiane, Urbach, Anja, Neves, Ricardo Melo, Witte, Otto W, Kiebel, Stefan J, Isbrandt, Dirk, Hübner, Christian A, Holthoff, Knut, Kirmse, Knut
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Sprache:eng
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