The Fibronectin Expression Determines the Distinct Progressions of Malignant Gliomas via Transforming Growth Factor-Beta Pathway

Due to the increasing incidence of malignant gliomas, particularly glioblastoma multiforme (GBM), a simple and reliable GBM diagnosis is needed to screen early the death-threaten patients. This study aimed to identify a protein that can be used to discriminate GBM from low-grade astrocytoma and eluc...

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Veröffentlicht in:	International journal of molecular sciences 2021-04, Vol.22 (7), p.3782
Hauptverfasser:	Chen, Chih-Wei, Yang, Cheng-Han, Lin, Yuan-Ho, Hou, Ya-Chin, Cheng, Tain-Junn, Chang, Sheng-Tsung, Huang, Yu-Hua, Chung, Shang-Ting, Chio, Chung-Ching, Shan, Yan-Shen, Cheng, Hung-Chi, Chang, Wen-Tsan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers Brain cancer Brain Neoplasms - diagnosis Brain Neoplasms - diagnostic imaging Brain Neoplasms - genetics Brain Neoplasms - metabolism Cancer Cancer therapies Cell adhesion & migration Databases, Nucleic Acid Female Fibronectin Fibronectins - biosynthesis Fibronectins - genetics Gene Expression Regulation, Neoplastic Glioblastoma Glioblastoma - diagnosis Glioblastoma - diagnostic imaging Glioblastoma - genetics Glioblastoma - metabolism Glioma Glycoproteins Growth factors Humans Kinases Male Malignancy Medical prognosis Mesenchyme Metastasis Middle Aged Mutation Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Patients Prognosis Proteins Signal Transduction Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism Transforming growth factor-b Tumorigenesis Tumors Vimentin
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