Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants' QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were eval...
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| Veröffentlicht in: | International journal of environmental research and public health 2021-03, Vol.18 (7), p.3503 |
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| creator | Funuyet-Salas, Jesús Pérez-San-Gregorio, María Ángeles Martín-Rodríguez, Agustín Romero-Gómez, Manuel |
| description | Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants' QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were evaluated in 307 biopsy-proven NAFLD patients with absence or presence of diabetes or obesity. QoL was compared with normality tables for the general Spanish population. Interactive effects were found in physical functioning (
= 0.008), role-physical (
= 0.016) and activity (
= 0.014). Diabetic patients reported worse scores when they were also obese and vice versa, that is, obese patients scored worse when they were also diabetic. Both diabetic and obese patients had lower QoL than those without metabolic pathology or the general population, and obese patients also reported more passive/avoidance coping. Active coping, positive reframing and acceptance predicted better QoL, while denial, self-blame, self-distraction, disengagement and religion predicted lower QoL. In conclusion, diabetes and obesity were associated with lower QoL in patients with NAFLD. Obesity was also associated with more passive/avoidance coping. Furthermore, passive/avoidance coping strategies predicted lower QoL than active, recommending modification of maladaptive coping strategies in future multidisciplinary NAFLD treatments. |
| doi_str_mv | 10.3390/ijerph18073503 |
| format | Article |
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= 0.008), role-physical (
= 0.016) and activity (
= 0.014). Diabetic patients reported worse scores when they were also obese and vice versa, that is, obese patients scored worse when they were also diabetic. Both diabetic and obese patients had lower QoL than those without metabolic pathology or the general population, and obese patients also reported more passive/avoidance coping. Active coping, positive reframing and acceptance predicted better QoL, while denial, self-blame, self-distraction, disengagement and religion predicted lower QoL. In conclusion, diabetes and obesity were associated with lower QoL in patients with NAFLD. Obesity was also associated with more passive/avoidance coping. Furthermore, passive/avoidance coping strategies predicted lower QoL than active, recommending modification of maladaptive coping strategies in future multidisciplinary NAFLD treatments.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph18073503</identifier><identifier>PMID: 33800585</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adaptation, Psychological ; Avoidance ; Biopsy ; Coping ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - epidemiology ; Fatty liver ; Humans ; Liver ; Liver diseases ; Metabolism ; Non-alcoholic Fatty Liver Disease ; Obesity ; Obesity - epidemiology ; Patients ; Quality of Life ; Questionnaires ; Regression analysis ; Sociodemographics ; Variables</subject><ispartof>International journal of environmental research and public health, 2021-03, Vol.18 (7), p.3503</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-101e245f5b1ecdb59d030c5e41167319cc9c03f2b3a2bd53370c94a98ff182a3</citedby><cites>FETCH-LOGICAL-c418t-101e245f5b1ecdb59d030c5e41167319cc9c03f2b3a2bd53370c94a98ff182a3</cites><orcidid>0000-0002-4133-140X ; 0000-0002-1308-5002</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036804/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036804/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33800585$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Funuyet-Salas, Jesús</creatorcontrib><creatorcontrib>Pérez-San-Gregorio, María Ángeles</creatorcontrib><creatorcontrib>Martín-Rodríguez, Agustín</creatorcontrib><creatorcontrib>Romero-Gómez, Manuel</creatorcontrib><title>Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants' QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were evaluated in 307 biopsy-proven NAFLD patients with absence or presence of diabetes or obesity. QoL was compared with normality tables for the general Spanish population. Interactive effects were found in physical functioning (
= 0.008), role-physical (
= 0.016) and activity (
= 0.014). Diabetic patients reported worse scores when they were also obese and vice versa, that is, obese patients scored worse when they were also diabetic. Both diabetic and obese patients had lower QoL than those without metabolic pathology or the general population, and obese patients also reported more passive/avoidance coping. Active coping, positive reframing and acceptance predicted better QoL, while denial, self-blame, self-distraction, disengagement and religion predicted lower QoL. In conclusion, diabetes and obesity were associated with lower QoL in patients with NAFLD. Obesity was also associated with more passive/avoidance coping. Furthermore, passive/avoidance coping strategies predicted lower QoL than active, recommending modification of maladaptive coping strategies in future multidisciplinary NAFLD treatments.</description><subject>Adaptation, Psychological</subject><subject>Avoidance</subject><subject>Biopsy</subject><subject>Coping</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Fatty liver</subject><subject>Humans</subject><subject>Liver</subject><subject>Liver diseases</subject><subject>Metabolism</subject><subject>Non-alcoholic Fatty Liver Disease</subject><subject>Obesity</subject><subject>Obesity - epidemiology</subject><subject>Patients</subject><subject>Quality of Life</subject><subject>Questionnaires</subject><subject>Regression analysis</subject><subject>Sociodemographics</subject><subject>Variables</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkUFrGzEQRkVpaNKk1x6LoJdenIx2VmttD4Vgx23AJARyF1rtyJZZS660G8i_7zpxQ5LTCObpIX0fY18FnCPWcOE3lHZroWCKEvADOxFVBZOyAvHx1fmYfc55A4CqrOpP7BhRAUglT5i5G0zn-0ceHV96R9yEls_izocV94HfxGA6G9ex85YvTD-CS_9Aic99JpPpJ78OrhsoWNob5t401FN-stw2lEfzGTtypsv05TBP2f3i6n72Z7K8_X09u1xObClUPxEgqCilk40g2zaybgHBSiqFqKYoamtrC-iKBk3RtBJxCrYuTa2cE6oweMp-PWt3Q7Ol1lLok-n0LvmtSY86Gq_fboJf61V80AqwUlCOgh8HQYp_B8q93vpsqetMoDhkXUhQcopVUYzo93foJg5pTGpPjZmXAEqM1PkzZVPMOZF7eYwAvS9Pvy1vvPDt9Rde8P9t4T_ENpYa</recordid><startdate>20210328</startdate><enddate>20210328</enddate><creator>Funuyet-Salas, Jesús</creator><creator>Pérez-San-Gregorio, María Ángeles</creator><creator>Martín-Rodríguez, Agustín</creator><creator>Romero-Gómez, Manuel</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4133-140X</orcidid><orcidid>https://orcid.org/0000-0002-1308-5002</orcidid></search><sort><creationdate>20210328</creationdate><title>Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity</title><author>Funuyet-Salas, Jesús ; Pérez-San-Gregorio, María Ángeles ; Martín-Rodríguez, Agustín ; Romero-Gómez, Manuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-101e245f5b1ecdb59d030c5e41167319cc9c03f2b3a2bd53370c94a98ff182a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adaptation, Psychological</topic><topic>Avoidance</topic><topic>Biopsy</topic><topic>Coping</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes mellitus (non-insulin dependent)</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Fatty liver</topic><topic>Humans</topic><topic>Liver</topic><topic>Liver diseases</topic><topic>Metabolism</topic><topic>Non-alcoholic Fatty Liver Disease</topic><topic>Obesity</topic><topic>Obesity - epidemiology</topic><topic>Patients</topic><topic>Quality of Life</topic><topic>Questionnaires</topic><topic>Regression analysis</topic><topic>Sociodemographics</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Funuyet-Salas, Jesús</creatorcontrib><creatorcontrib>Pérez-San-Gregorio, María Ángeles</creatorcontrib><creatorcontrib>Martín-Rodríguez, Agustín</creatorcontrib><creatorcontrib>Romero-Gómez, Manuel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Funuyet-Salas, Jesús</au><au>Pérez-San-Gregorio, María Ángeles</au><au>Martín-Rodríguez, Agustín</au><au>Romero-Gómez, Manuel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2021-03-28</date><risdate>2021</risdate><volume>18</volume><issue>7</issue><spage>3503</spage><pages>3503-</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants' QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were evaluated in 307 biopsy-proven NAFLD patients with absence or presence of diabetes or obesity. QoL was compared with normality tables for the general Spanish population. Interactive effects were found in physical functioning (
= 0.008), role-physical (
= 0.016) and activity (
= 0.014). Diabetic patients reported worse scores when they were also obese and vice versa, that is, obese patients scored worse when they were also diabetic. Both diabetic and obese patients had lower QoL than those without metabolic pathology or the general population, and obese patients also reported more passive/avoidance coping. Active coping, positive reframing and acceptance predicted better QoL, while denial, self-blame, self-distraction, disengagement and religion predicted lower QoL. In conclusion, diabetes and obesity were associated with lower QoL in patients with NAFLD. Obesity was also associated with more passive/avoidance coping. Furthermore, passive/avoidance coping strategies predicted lower QoL than active, recommending modification of maladaptive coping strategies in future multidisciplinary NAFLD treatments.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33800585</pmid><doi>10.3390/ijerph18073503</doi><orcidid>https://orcid.org/0000-0002-4133-140X</orcidid><orcidid>https://orcid.org/0000-0002-1308-5002</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adaptation, Psychological Avoidance Biopsy Coping Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - epidemiology Fatty liver Humans Liver Liver diseases Metabolism Non-alcoholic Fatty Liver Disease Obesity Obesity - epidemiology Patients Quality of Life Questionnaires Regression analysis Sociodemographics Variables |
| title | Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity |
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