Performance of the rapid high-throughput automated electrochemiluminescence immunoassay targeting total antibodies to the SARS-CoV-2 spike protein receptor binding domain in comparison to the neutralization assay

•First evaluation of Elecsys-S against neutralization on 357 post−COVID-19 patients.•Moderate Elecsys-S/neutralization agreement established (Cohen’s kappa 0.56).•72 % of convalescent-patients contained neutralization antibodies (NAb).•Elecsys-S’s cut-off value for reasonable prediction of NAb prese...

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