A novel SHAPE reagent enables the analysis of RNA structure in living cells with unprecedented accuracy

Abstract Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need. We introduce here 2-aminopyridine-3-carbo...

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Veröffentlicht in:	Nucleic acids research 2021-04, Vol.49 (6), p.e34-e34
Hauptverfasser:	Marinus, Tycho, Fessler, Adam B, Ogle, Craig A, Incarnato, Danny
Format:	Artikel
Sprache:	eng
Schlagworte:	HEK293 Cells Humans Indicators and Reagents Methods Online Nucleic Acid Conformation RNA - chemistry RNA-Directed DNA Polymerase
Online-Zugang:	Volltext
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