Phenotypic profiling of mGlu7 knockout mice reveals new implications for neurodevelopmental disorders

Neurodevelopmental disorders are characterized by deficits in communication, cognition, attention, social behavior and/or motor control. Previous studies have pointed to the involvement of genes that regulate synaptic structure and function in the pathogenesis of these disorders. One such gene, GRM7...

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2020-09, Vol.19 (7), p.e12654-n/a
Hauptverfasser:	Fisher, Nicole M., Gould, Robert W., Gogliotti, Rocco G., McDonald, Annalise J., Badivuku, Hana, Chennareddy, Susmita, Buch, Aditi B., Moore, Annah M., Jenkins, Matthew T., Robb, W. Hudson, Lindsley, Craig W., Jones, Carrie K., Conn, P. Jeffrey, Niswender, Colleen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADHD Amphetamines ASD Associative learning Attention deficit hyperactivity disorder Autism Cognition EEG Epilepsy Glutamic acid receptors Glutamic acid receptors (metabotropic) GRM7 mGlu7 Motor skill learning Motor task performance Neurodevelopmental disorders Neurotransmitter release Phenotypes Population studies Rett syndrome seizures Sleep Social behavior Social discrimination learning Social interactions Structure-function relationships
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