Antibody Binding Epitope Mapping (AbMap) of Hundred Antibodies in a Single Run

Antibodies play essential roles in both diagnostics and therapeutics. Epitope mapping is essential to understand how an antibody works and to protect intellectual property. Given the millions of antibodies for which epitope information is lacking, there is a need for high-throughput epitope mapping....

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Veröffentlicht in:	Molecular & cellular proteomics 2021-01, Vol.20, p.100059-100059, Article 100059
Hauptverfasser:	Qi, Huan, Ma, Mingliang, Hu, Chuansheng, Xu, Zhao-wei, Wu, Fan-lin, Wang, Nan, Lai, Dan-yun, Li, Yang, Zhang, Hainan, Jiang, He-wei, Meng, Qing-feng, Guo, Shujuan, Kang, Yani, Zhao, Xiaodong, Li, Hua, Tao, Sheng-ce
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology Antibodies, Monoclonal - metabolism Antibodies, Viral - metabolism COVID-19 COVID-19 - immunology Enzyme-Linked Immunosorbent Assay epitope mapping Epitope Mapping - methods Epitopes - metabolism Escherichia coli Proteins - immunology High-Throughput Nucleotide Sequencing Humans Immune Sera - blood Immune Sera - immunology next-generation sequencing Peptide Library phage display random peptide library Spike Glycoprotein, Coronavirus - immunology
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