The xenobiotic receptors PXR and CAR in liver physiology, an update

Pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are two nuclear receptors that are well-known for their roles in xenobiotic detoxification by regulating the expression of drug-metabolizing enzymes and transporters. In addition to metabolizing drugs and other xenobiotics, the sam...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2021-06, Vol.1867 (6), p.166101-166101, Article 166101
Hauptverfasser:	Cai, Xinran, Young, Gregory M., Xie, Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile acid homeostasis CAR Cell proliferation Energy metabolism PXR Xenobiotic receptors
Online-Zugang:	Volltext
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