In Vitro Release Testing of Acyclovir Topical Formulations Using Immersion Cells

The objective of the study was to reinforce the applicability of the immersion cells for the in vitro release testing (IVRT) of topical formulations by using marketed acyclovir 5% cream formulation (Cream 1) as a model. The method employing the immersion cells was optimized by studying the effect of...

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Veröffentlicht in:	Assay and drug development technologies 2021-03, Vol.19 (2), p.75-84
Hauptverfasser:	Kulkarni, Madhur, Potdar, Shrikant, Date, Abhijit A, Marfatiya, Aditya
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir Acyclovir - administration & dosage Acyclovir - chemistry Administration, Topical Aging Antiviral Agents - administration & dosage Antiviral Agents - chemistry Antiviral drugs Cell size Cellulose esters Cellulose nitrate Composition Control stability Drug Compounding Drug Liberation Humans Immersion Membranes Membranes, Artificial Ointments - administration & dosage Ointments - chemistry Product development Quality assessment Quality control Semisolids Stability analysis Submerging Temperature Topical medication
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