Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes

Trimethylamine N-oxide (TMAO), choline and betaine serum levels have been associated with metabolic diseases including type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD). These associations could be mediated by insulin resistance. However, the relationships among these metabolites,...

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Veröffentlicht in:	Diabetes & metabolism 2021-03, Vol.47 (2), p.101183-101183, Article 101183
Hauptverfasser:	León-Mimila, P., Villamil-Ramírez, H., Li, X.S., Shih, D.M., Hui, S.T., Ocampo-Medina, E., López-Contreras, B., Morán-Ramos, S., Olivares-Arevalo, M., Grandini-Rosales, P., Macías-Kauffer, L., González-González, I., Hernández-Pando, R., Gómez-Pérez, F., Campos-Pérez, F., Aguilar-Salinas, C., Larrieta-Carrasco, E., Villarreal-Molina, T., Wang, Z., Lusis, A.J., Hazen, S.L., Huertas-Vazquez, A., Canizales-Quinteros, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Betaine - blood Bile Acids and Salts - blood Biomarkers - blood Biopsy Choline - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Female Humans Insulin Resistance Liver - pathology Male Methylamines - blood Mexican Americans Middle Aged Non-alcoholic fatty liver disease Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - epidemiology Obesity - complications Obesity - epidemiology TMAO Type 2 diabetes
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