Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa

Bloodstream infections caused by nontyphoidal Salmonella are a major public health concern in Africa, causing ~49,600 deaths every year. The most common Salmonella enterica pathovariant associated with invasive nontyphoidal Salmonella disease is Salmonella Typhimurium sequence type (ST)313. It has b...

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Veröffentlicht in:	Nature microbiology 2021-03, Vol.6 (3), p.327-338
Hauptverfasser:	Pulford, Caisey V., Perez-Sepulveda, Blanca M., Canals, Rocío, Bevington, Jessica A., Bengtsson, Rebecca J., Wenner, Nicolas, Rodwell, Ella V., Kumwenda, Benjamin, Zhu, Xiaojun, Bennett, Rebecca J., Stenhouse, George E., Malaka De Silva, P., Webster, Hermione J., Bengoechea, Jose A., Dumigan, Amy, Tran-Dien, Alicia, Prakash, Reenesh, Banda, Happy C., Alufandika, Lovemore, Mautanga, Mike P., Bowers-Barnard, Arthur, Beliavskaia, Alexandra Y., Predeus, Alexander V., Rowe, Will P. M., Darby, Alistair C., Hall, Neil, Weill, François-Xavier, Gordon, Melita A., Feasey, Nicholas A., Baker, Kate S., Hinton, Jay C. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	45 45/23 631/114 631/114/2785 631/114/739 631/181/735 631/181/757 82/58 Africa - epidemiology Antimicrobial resistance Biomedical and Life Sciences Drug Resistance, Bacterial Evolution Evolution, Molecular Gastrointestinal diseases Genetic Variation Genome, Bacterial - genetics Genomes Genomic analysis Genotype Humans Infectious Diseases Life Sciences Medical Microbiology Microbiology Parasitology Phenotype Phylogeny Plasmids - genetics Pseudogenes Public health Salmonella Salmonella Infections - epidemiology Salmonella Infections - microbiology Salmonella Typhimurium Salmonella typhimurium - genetics Salmonella typhimurium - isolation & purification Salmonella typhimurium - pathogenicity Salmonella typhimurium - physiology Sepsis - epidemiology Sepsis - microbiology Sepsis - transmission Virology Virulence
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