Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data

We have developed periscope, a tool for the detection and quantification of subgenomic RNA (sgRNA) in SARS-CoV-2 genomic sequence data. The translation of the SARS-CoV-2 RNA genome for most open reading frames (ORFs) occurs via RNA intermediates termed "subgenomic RNAs." sgRNAs are produce...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genome research 2021-04, Vol.31 (4), p.645-658
Hauptverfasser:	Parker, Matthew D, Lindsey, Benjamin B, Leary, Shay, Gaudieri, Silvana, Chopra, Abha, Wyles, Matthew, Angyal, Adrienn, Green, Luke R, Parsons, Paul, Tucker, Rachel M, Brown, Rebecca, Groves, Danielle, Johnson, Katie, Carrilero, Laura, Heffer, Joe, Partridge, David G, Evans, Cariad, Raza, Mohammad, Keeley, Alexander J, Smith, Nikki, Filipe, Ana Da Silva, Shepherd, James G, Davis, Chris, Bennett, Sahan, Sreenu, Vattipally B, Kohl, Alain, Aranday-Cortes, Elihu, Tong, Lily, Nichols, Jenna, Thomson, Emma C, Wang, Dennis, Mallal, Simon, de Silva, Thushan I
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions ACE2 Angiotensin-converting enzyme 2 Animals Base Sequence Cell lines Chlorocebus aethiops Codons COVID-19 Genome, Viral Genomics Homology Humans Intermediates Limit of Detection Method Nucleotide sequence Open reading frames Regulatory sequences Ribonucleic acid RNA RNA, Viral - genetics SARS-CoV-2 - genetics Sequence Analysis, RNA - methods Severe acute respiratory syndrome coronavirus 2 Transcription Vero Cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!