Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms
ISAT provided valuable data on patient outcome after endovascular coiling and surgical clipping of ruptured aneurysms. The purpose of this study was to retrospectively review the ≥1-year outcome (in terms of survival, independence, and rebleeding) of patients who were treated in a routine clinical s...
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Veröffentlicht in: | American journal of neuroradiology : AJNR 2011-03, Vol.32 (3), p.570-575 |
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container_title | American journal of neuroradiology : AJNR |
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description | ISAT provided valuable data on patient outcome after endovascular coiling and surgical clipping of ruptured aneurysms. The purpose of this study was to retrospectively review the ≥1-year outcome (in terms of survival, independence, and rebleeding) of patients who were treated in a routine clinical setting.
Records of patients presenting with an SAH from a ruptured aneurysm between 2000 and 2008 were reviewed. The 403 patients who met the inclusion criteria harbored 443 treated aneurysms; 173 were managed surgically and 230 by endovascular means. Mean clinical follow-up was 33.9 months (range, 12-106 months).
The pretreatment clinical condition according to the HH was significantly better in the surgically treated patients (P = .018). Death occurred in 11.6% after surgery and in 17.4% after endovascular treatment (P = .104). Of the surviving patients in the surgical and endovascular groups, 80.3% and 87.2%, respectively, were able to live independently with grades 0-2 on the mRS (P = .084). Complete aneurysm occlusion was achieved significantly more often after surgical treatment (P < .001). Rebleeding occurred in 3.1% and 2.3% of the patients after surgical treatment and endovascular coiling, respectively. The occurrence of a residual aneurysm at the end of a coiling procedure was significantly related to the frequency of rebleeding (P = .007).
The management of patients with intracranial aneurysms in a routine clinical setting shows good and comparable rates of mortality and independence. Coiling results in lower rates of complete aneurysm occlusion. Postcoiling angiography showing a residual aneurysm is a good predictor of the risk of rebleeding. |
doi_str_mv | 10.3174/ajnr.A2326 |
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Records of patients presenting with an SAH from a ruptured aneurysm between 2000 and 2008 were reviewed. The 403 patients who met the inclusion criteria harbored 443 treated aneurysms; 173 were managed surgically and 230 by endovascular means. Mean clinical follow-up was 33.9 months (range, 12-106 months).
The pretreatment clinical condition according to the HH was significantly better in the surgically treated patients (P = .018). Death occurred in 11.6% after surgery and in 17.4% after endovascular treatment (P = .104). Of the surviving patients in the surgical and endovascular groups, 80.3% and 87.2%, respectively, were able to live independently with grades 0-2 on the mRS (P = .084). Complete aneurysm occlusion was achieved significantly more often after surgical treatment (P < .001). Rebleeding occurred in 3.1% and 2.3% of the patients after surgical treatment and endovascular coiling, respectively. The occurrence of a residual aneurysm at the end of a coiling procedure was significantly related to the frequency of rebleeding (P = .007).
The management of patients with intracranial aneurysms in a routine clinical setting shows good and comparable rates of mortality and independence. Coiling results in lower rates of complete aneurysm occlusion. Postcoiling angiography showing a residual aneurysm is a good predictor of the risk of rebleeding.</description><identifier>ISSN: 0195-6108</identifier><identifier>EISSN: 1936-959X</identifier><identifier>DOI: 10.3174/ajnr.A2326</identifier><identifier>PMID: 21349958</identifier><identifier>CODEN: AAJNDL</identifier><language>eng</language><publisher>Oak Brook, IL: American Society of Neuroradiology</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aneurysm, Ruptured - epidemiology ; Biological and medical sciences ; Electrodiagnosis. Electric activity recording ; Embolization, Therapeutic - statistics & numerical data ; Female ; Humans ; Interventional ; Intracranial Aneurysm - epidemiology ; Intracranial Aneurysm - surgery ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Nervous system ; Netherlands - epidemiology ; Neurosurgical Procedures - statistics & numerical data ; Prevalence ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Risk Assessment ; Risk Factors ; Stents - statistics & numerical data ; Young Adult</subject><ispartof>American journal of neuroradiology : AJNR, 2011-03, Vol.32 (3), p.570-575</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © American Society of Neuroradiology 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-f2920bb5cddd1a37881215642311e109f7e425dff5d1f9af9973014f5448fc743</citedby><cites>FETCH-LOGICAL-c439t-f2920bb5cddd1a37881215642311e109f7e425dff5d1f9af9973014f5448fc743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013111/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013111/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23982042$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21349958$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KLOMPENHOUWER, E. G</creatorcontrib><creatorcontrib>DINGS, J. T. A</creatorcontrib><creatorcontrib>VAN OOSTENBRUGGE, R. J</creatorcontrib><creatorcontrib>OEI, S</creatorcontrib><creatorcontrib>WILMINK, J. T</creatorcontrib><creatorcontrib>VAN ZWAM, W. H</creatorcontrib><title>Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms</title><title>American journal of neuroradiology : AJNR</title><addtitle>AJNR Am J Neuroradiol</addtitle><description>ISAT provided valuable data on patient outcome after endovascular coiling and surgical clipping of ruptured aneurysms. The purpose of this study was to retrospectively review the ≥1-year outcome (in terms of survival, independence, and rebleeding) of patients who were treated in a routine clinical setting.
Records of patients presenting with an SAH from a ruptured aneurysm between 2000 and 2008 were reviewed. The 403 patients who met the inclusion criteria harbored 443 treated aneurysms; 173 were managed surgically and 230 by endovascular means. Mean clinical follow-up was 33.9 months (range, 12-106 months).
The pretreatment clinical condition according to the HH was significantly better in the surgically treated patients (P = .018). Death occurred in 11.6% after surgery and in 17.4% after endovascular treatment (P = .104). Of the surviving patients in the surgical and endovascular groups, 80.3% and 87.2%, respectively, were able to live independently with grades 0-2 on the mRS (P = .084). Complete aneurysm occlusion was achieved significantly more often after surgical treatment (P < .001). Rebleeding occurred in 3.1% and 2.3% of the patients after surgical treatment and endovascular coiling, respectively. The occurrence of a residual aneurysm at the end of a coiling procedure was significantly related to the frequency of rebleeding (P = .007).
The management of patients with intracranial aneurysms in a routine clinical setting shows good and comparable rates of mortality and independence. Coiling results in lower rates of complete aneurysm occlusion. Postcoiling angiography showing a residual aneurysm is a good predictor of the risk of rebleeding.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aneurysm, Ruptured - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Electrodiagnosis. Electric activity recording</subject><subject>Embolization, Therapeutic - statistics & numerical data</subject><subject>Female</subject><subject>Humans</subject><subject>Interventional</subject><subject>Intracranial Aneurysm - epidemiology</subject><subject>Intracranial Aneurysm - surgery</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous system</subject><subject>Netherlands - epidemiology</subject><subject>Neurosurgical Procedures - statistics & numerical data</subject><subject>Prevalence</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Stents - statistics & numerical data</subject><subject>Young Adult</subject><issn>0195-6108</issn><issn>1936-959X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkdFrFDEQxoMo9jx98Q-QfZGCsDWTbHaTF-E4zrZQEGwF30IumZwpu9kz2S32vzdnz6pPPs3D_Oabb-Yj5DXQMw5d897cxnS2Ypy1T8gCFG9rJdTXp2RBQYm6BSpPyIucbymlQnXsOTlhwBulhFyQ7XWIux7rNcYJU7X5sccUMFqsRl9dz2kXrOkrE121iW68M9nOvUnVTUIzDWXmgH2e99Oc0FWXcUrGJhNDmVlFnNN9HvJL8sybPuOrY12SLx83N-uL-urT-eV6dVXbhqup9kwxut0K65wDwzspgYFoG8YBEKjyHTZMOO-FA6-MV6rjFBovmkZ62zV8ST486O7n7YDO4sFNr_cpDCbd69EE_W8nhm96N95pSaHsgCJwehRI4_cZ86SHkC32vYk4zlkr2oGQoNr_klJ05RpRvC_JuwfSpjHnhP7RD1B9SE8f0tO_0ivwm78veER_x1WAt0egBGF6X15tQ_7DcSUZLVt_ApVQpH4</recordid><startdate>20110301</startdate><enddate>20110301</enddate><creator>KLOMPENHOUWER, E. G</creator><creator>DINGS, J. T. A</creator><creator>VAN OOSTENBRUGGE, R. J</creator><creator>OEI, S</creator><creator>WILMINK, J. T</creator><creator>VAN ZWAM, W. H</creator><general>American Society of Neuroradiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope><scope>5PM</scope></search><sort><creationdate>20110301</creationdate><title>Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms</title><author>KLOMPENHOUWER, E. G ; DINGS, J. T. A ; VAN OOSTENBRUGGE, R. J ; OEI, S ; WILMINK, J. T ; VAN ZWAM, W. H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-f2920bb5cddd1a37881215642311e109f7e425dff5d1f9af9973014f5448fc743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aneurysm, Ruptured - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Electrodiagnosis. Electric activity recording</topic><topic>Embolization, Therapeutic - statistics & numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Interventional</topic><topic>Intracranial Aneurysm - epidemiology</topic><topic>Intracranial Aneurysm - surgery</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nervous system</topic><topic>Netherlands - epidemiology</topic><topic>Neurosurgical Procedures - statistics & numerical data</topic><topic>Prevalence</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Stents - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KLOMPENHOUWER, E. G</creatorcontrib><creatorcontrib>DINGS, J. T. A</creatorcontrib><creatorcontrib>VAN OOSTENBRUGGE, R. J</creatorcontrib><creatorcontrib>OEI, S</creatorcontrib><creatorcontrib>WILMINK, J. T</creatorcontrib><creatorcontrib>VAN ZWAM, W. H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of neuroradiology : AJNR</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KLOMPENHOUWER, E. G</au><au>DINGS, J. T. A</au><au>VAN OOSTENBRUGGE, R. J</au><au>OEI, S</au><au>WILMINK, J. T</au><au>VAN ZWAM, W. H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms</atitle><jtitle>American journal of neuroradiology : AJNR</jtitle><addtitle>AJNR Am J Neuroradiol</addtitle><date>2011-03-01</date><risdate>2011</risdate><volume>32</volume><issue>3</issue><spage>570</spage><epage>575</epage><pages>570-575</pages><issn>0195-6108</issn><eissn>1936-959X</eissn><coden>AAJNDL</coden><abstract>ISAT provided valuable data on patient outcome after endovascular coiling and surgical clipping of ruptured aneurysms. The purpose of this study was to retrospectively review the ≥1-year outcome (in terms of survival, independence, and rebleeding) of patients who were treated in a routine clinical setting.
Records of patients presenting with an SAH from a ruptured aneurysm between 2000 and 2008 were reviewed. The 403 patients who met the inclusion criteria harbored 443 treated aneurysms; 173 were managed surgically and 230 by endovascular means. Mean clinical follow-up was 33.9 months (range, 12-106 months).
The pretreatment clinical condition according to the HH was significantly better in the surgically treated patients (P = .018). Death occurred in 11.6% after surgery and in 17.4% after endovascular treatment (P = .104). Of the surviving patients in the surgical and endovascular groups, 80.3% and 87.2%, respectively, were able to live independently with grades 0-2 on the mRS (P = .084). Complete aneurysm occlusion was achieved significantly more often after surgical treatment (P < .001). Rebleeding occurred in 3.1% and 2.3% of the patients after surgical treatment and endovascular coiling, respectively. The occurrence of a residual aneurysm at the end of a coiling procedure was significantly related to the frequency of rebleeding (P = .007).
The management of patients with intracranial aneurysms in a routine clinical setting shows good and comparable rates of mortality and independence. Coiling results in lower rates of complete aneurysm occlusion. Postcoiling angiography showing a residual aneurysm is a good predictor of the risk of rebleeding.</abstract><cop>Oak Brook, IL</cop><pub>American Society of Neuroradiology</pub><pmid>21349958</pmid><doi>10.3174/ajnr.A2326</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Aneurysm, Ruptured - epidemiology Biological and medical sciences Electrodiagnosis. Electric activity recording Embolization, Therapeutic - statistics & numerical data Female Humans Interventional Intracranial Aneurysm - epidemiology Intracranial Aneurysm - surgery Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Nervous system Netherlands - epidemiology Neurosurgical Procedures - statistics & numerical data Prevalence Radiodiagnosis. Nmr imagery. Nmr spectrometry Risk Assessment Risk Factors Stents - statistics & numerical data Young Adult |
title | Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms |
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