Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors
Diagnostic test accuracy studies for ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy have shown inconclusive results due to their heterogenous study designs. Our aim was to compare the diagnostic accuracy of ultrasonography-guided fine-needle aspiration ve...
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| Veröffentlicht in: | American journal of neuroradiology : AJNR 2015-06, Vol.36 (6), p.1188-1193 |
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| creator | Eom, H-J Lee, J H Ko, M-S Choi, Y J Yoon, R G Cho, K J Nam, S Y Baek, J H |
| description | Diagnostic test accuracy studies for ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy have shown inconclusive results due to their heterogenous study designs. Our aim was to compare the diagnostic accuracy of ultrasonography-guided fine-needle aspiration versus ultrasonography-guided core needle biopsy for detecting malignant tumors of the salivary gland and for the tissue-specific diagnosis of salivary gland tumors in a single tertiary hospital.
This retrospective study was approved by our institutional review board and informed consent was waived. Four hundred twelve patients who underwent ultrasonography-guided fine-needle aspiration (n = 155) or ultrasonography-guided core needle biopsy (n = 257) with subsequent surgical confirmation or clinical follow-up were enrolled. We compared the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy regarding malignant salivary gland tumors and the correct tissue-specific diagnosis of benign and malignant tumors. We also tested the difference between these procedures according to the operator's experience and lesion characteristics.
The inconclusive rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 19% and 4%, respectively (P < .001). The overall accuracy of ultrasonography-guided core needle biopsy for diagnosing malignant tumors was significantly higher than that of ultrasonography-guided fine-needle aspiration (P = .024). The correct tissue-specific diagnosis rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 95% versus 97% for benign tumors (P = .648) and 67% versus 80% for malignant tumors (P = .310). Trainees showed significantly lower accuracy with ultrasonography-guided fine-needle aspiration than with ultrasonography-guided core needle biopsy for diagnosing malignant tumors (P = .021). There was no difference between the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy according to the internal composition of the lesions. There were no complications requiring intervention or hospitalization in our patients.
Ultrasonography-guided core needle biopsy is superior to ultrasonography-guided fine-needle aspiration in detecting and characterizing malignant tumors of the salivary gland and could emerge as the diagnostic method of choice |
| doi_str_mv | 10.3174/ajnr.A4247 |
| format | Article |
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This retrospective study was approved by our institutional review board and informed consent was waived. Four hundred twelve patients who underwent ultrasonography-guided fine-needle aspiration (n = 155) or ultrasonography-guided core needle biopsy (n = 257) with subsequent surgical confirmation or clinical follow-up were enrolled. We compared the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy regarding malignant salivary gland tumors and the correct tissue-specific diagnosis of benign and malignant tumors. We also tested the difference between these procedures according to the operator's experience and lesion characteristics.
The inconclusive rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 19% and 4%, respectively (P < .001). The overall accuracy of ultrasonography-guided core needle biopsy for diagnosing malignant tumors was significantly higher than that of ultrasonography-guided fine-needle aspiration (P = .024). The correct tissue-specific diagnosis rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 95% versus 97% for benign tumors (P = .648) and 67% versus 80% for malignant tumors (P = .310). Trainees showed significantly lower accuracy with ultrasonography-guided fine-needle aspiration than with ultrasonography-guided core needle biopsy for diagnosing malignant tumors (P = .021). There was no difference between the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy according to the internal composition of the lesions. There were no complications requiring intervention or hospitalization in our patients.
Ultrasonography-guided core needle biopsy is superior to ultrasonography-guided fine-needle aspiration in detecting and characterizing malignant tumors of the salivary gland and could emerge as the diagnostic method of choice for patients presenting with a salivary gland mass.</description><identifier>ISSN: 0195-6108</identifier><identifier>EISSN: 1936-959X</identifier><identifier>DOI: 10.3174/ajnr.A4247</identifier><identifier>PMID: 25678480</identifier><language>eng</language><publisher>United States: American Society of Neuroradiology</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biopsy, Fine-Needle - methods ; Biopsy, Large-Core Needle - methods ; Child ; Female ; Head & Neck ; Humans ; Informed Consent ; Male ; Middle Aged ; Retrospective Studies ; Salivary Gland Neoplasms - pathology ; Salivary Glands - pathology ; Sensitivity and Specificity ; Ultrasonography, Interventional - methods ; Young Adult</subject><ispartof>American journal of neuroradiology : AJNR, 2015-06, Vol.36 (6), p.1188-1193</ispartof><rights>2015 by American Journal of Neuroradiology.</rights><rights>2015 by American Journal of Neuroradiology 2015 American Journal of Neuroradiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-d67d469fac3164a6ac33ef9cab98c339183d2e008bd3accf7b0918f75eebfcc3</citedby><cites>FETCH-LOGICAL-c411t-d67d469fac3164a6ac33ef9cab98c339183d2e008bd3accf7b0918f75eebfcc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013020/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013020/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25678480$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eom, H-J</creatorcontrib><creatorcontrib>Lee, J H</creatorcontrib><creatorcontrib>Ko, M-S</creatorcontrib><creatorcontrib>Choi, Y J</creatorcontrib><creatorcontrib>Yoon, R G</creatorcontrib><creatorcontrib>Cho, K J</creatorcontrib><creatorcontrib>Nam, S Y</creatorcontrib><creatorcontrib>Baek, J H</creatorcontrib><title>Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors</title><title>American journal of neuroradiology : AJNR</title><addtitle>AJNR Am J Neuroradiol</addtitle><description>Diagnostic test accuracy studies for ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy have shown inconclusive results due to their heterogenous study designs. Our aim was to compare the diagnostic accuracy of ultrasonography-guided fine-needle aspiration versus ultrasonography-guided core needle biopsy for detecting malignant tumors of the salivary gland and for the tissue-specific diagnosis of salivary gland tumors in a single tertiary hospital.
This retrospective study was approved by our institutional review board and informed consent was waived. Four hundred twelve patients who underwent ultrasonography-guided fine-needle aspiration (n = 155) or ultrasonography-guided core needle biopsy (n = 257) with subsequent surgical confirmation or clinical follow-up were enrolled. We compared the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy regarding malignant salivary gland tumors and the correct tissue-specific diagnosis of benign and malignant tumors. We also tested the difference between these procedures according to the operator's experience and lesion characteristics.
The inconclusive rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 19% and 4%, respectively (P < .001). The overall accuracy of ultrasonography-guided core needle biopsy for diagnosing malignant tumors was significantly higher than that of ultrasonography-guided fine-needle aspiration (P = .024). The correct tissue-specific diagnosis rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 95% versus 97% for benign tumors (P = .648) and 67% versus 80% for malignant tumors (P = .310). Trainees showed significantly lower accuracy with ultrasonography-guided fine-needle aspiration than with ultrasonography-guided core needle biopsy for diagnosing malignant tumors (P = .021). There was no difference between the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy according to the internal composition of the lesions. There were no complications requiring intervention or hospitalization in our patients.
Ultrasonography-guided core needle biopsy is superior to ultrasonography-guided fine-needle aspiration in detecting and characterizing malignant tumors of the salivary gland and could emerge as the diagnostic method of choice for patients presenting with a salivary gland mass.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biopsy, Fine-Needle - methods</subject><subject>Biopsy, Large-Core Needle - methods</subject><subject>Child</subject><subject>Female</subject><subject>Head & Neck</subject><subject>Humans</subject><subject>Informed Consent</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Salivary Gland Neoplasms - pathology</subject><subject>Salivary Glands - pathology</subject><subject>Sensitivity and Specificity</subject><subject>Ultrasonography, Interventional - methods</subject><subject>Young Adult</subject><issn>0195-6108</issn><issn>1936-959X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUk1rFTEUDaLY1-rGHyBZijA1mcxHshHKQ6tQcNOFu5BJbualzCRjkim839U_aKZ9Fl25uiHng3O5B6F3lFwy2jef1J2Pl1dN3fQv0I4K1lWiFT9foh2hoq06SvgZOk_pjhDSir5-jc7qtut5w8kOPezDvKjoUvA4WGydh8oDmAmwSouLKruCKG-wDhHwCRpcWNIRr95AxOuUoyr6MEa1HJzG4-qM8hqwDREbyKCz8yOe1eRGX4Djo98G5gPg7FJaoUoLaGeL2jg1-pBc2vKkorlX8YjHadPkdQ4xvUGvrJoSvD3NC3T79cvt_lt18-P6-_7qptINpbkyXW-aTlilGe0a1ZXJwAqtBsHLU1DOTA2E8MEwpbXtB1L-bN8CDFZrdoE-P9ku6zCD0eDLnpNcoptLIhmUk_8i3h3kGO4lJ5SRmhSDDyeDGH6tkLKcXdIwlVUgrElSTnjH6law_1M7zkk5J-OF-vGJqmNIKYJ9TkSJ3Pogtz7Ixz4U8vu_d3im_ikA-w25x7jS</recordid><startdate>201506</startdate><enddate>201506</enddate><creator>Eom, H-J</creator><creator>Lee, J H</creator><creator>Ko, M-S</creator><creator>Choi, Y J</creator><creator>Yoon, R G</creator><creator>Cho, K J</creator><creator>Nam, S Y</creator><creator>Baek, J H</creator><general>American Society of Neuroradiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope><scope>5PM</scope></search><sort><creationdate>201506</creationdate><title>Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors</title><author>Eom, H-J ; Lee, J H ; Ko, M-S ; Choi, Y J ; Yoon, R G ; Cho, K J ; Nam, S Y ; Baek, J H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-d67d469fac3164a6ac33ef9cab98c339183d2e008bd3accf7b0918f75eebfcc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biopsy, Fine-Needle - methods</topic><topic>Biopsy, Large-Core Needle - methods</topic><topic>Child</topic><topic>Female</topic><topic>Head & Neck</topic><topic>Humans</topic><topic>Informed Consent</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Salivary Gland Neoplasms - pathology</topic><topic>Salivary Glands - pathology</topic><topic>Sensitivity and Specificity</topic><topic>Ultrasonography, Interventional - methods</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eom, H-J</creatorcontrib><creatorcontrib>Lee, J H</creatorcontrib><creatorcontrib>Ko, M-S</creatorcontrib><creatorcontrib>Choi, Y J</creatorcontrib><creatorcontrib>Yoon, R G</creatorcontrib><creatorcontrib>Cho, K J</creatorcontrib><creatorcontrib>Nam, S Y</creatorcontrib><creatorcontrib>Baek, J H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of neuroradiology : AJNR</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eom, H-J</au><au>Lee, J H</au><au>Ko, M-S</au><au>Choi, Y J</au><au>Yoon, R G</au><au>Cho, K J</au><au>Nam, S Y</au><au>Baek, J H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors</atitle><jtitle>American journal of neuroradiology : AJNR</jtitle><addtitle>AJNR Am J Neuroradiol</addtitle><date>2015-06</date><risdate>2015</risdate><volume>36</volume><issue>6</issue><spage>1188</spage><epage>1193</epage><pages>1188-1193</pages><issn>0195-6108</issn><eissn>1936-959X</eissn><abstract>Diagnostic test accuracy studies for ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy have shown inconclusive results due to their heterogenous study designs. Our aim was to compare the diagnostic accuracy of ultrasonography-guided fine-needle aspiration versus ultrasonography-guided core needle biopsy for detecting malignant tumors of the salivary gland and for the tissue-specific diagnosis of salivary gland tumors in a single tertiary hospital.
This retrospective study was approved by our institutional review board and informed consent was waived. Four hundred twelve patients who underwent ultrasonography-guided fine-needle aspiration (n = 155) or ultrasonography-guided core needle biopsy (n = 257) with subsequent surgical confirmation or clinical follow-up were enrolled. We compared the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy regarding malignant salivary gland tumors and the correct tissue-specific diagnosis of benign and malignant tumors. We also tested the difference between these procedures according to the operator's experience and lesion characteristics.
The inconclusive rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 19% and 4%, respectively (P < .001). The overall accuracy of ultrasonography-guided core needle biopsy for diagnosing malignant tumors was significantly higher than that of ultrasonography-guided fine-needle aspiration (P = .024). The correct tissue-specific diagnosis rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 95% versus 97% for benign tumors (P = .648) and 67% versus 80% for malignant tumors (P = .310). Trainees showed significantly lower accuracy with ultrasonography-guided fine-needle aspiration than with ultrasonography-guided core needle biopsy for diagnosing malignant tumors (P = .021). There was no difference between the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy according to the internal composition of the lesions. There were no complications requiring intervention or hospitalization in our patients.
Ultrasonography-guided core needle biopsy is superior to ultrasonography-guided fine-needle aspiration in detecting and characterizing malignant tumors of the salivary gland and could emerge as the diagnostic method of choice for patients presenting with a salivary gland mass.</abstract><cop>United States</cop><pub>American Society of Neuroradiology</pub><pmid>25678480</pmid><doi>10.3174/ajnr.A4247</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Biopsy, Fine-Needle - methods Biopsy, Large-Core Needle - methods Child Female Head & Neck Humans Informed Consent Male Middle Aged Retrospective Studies Salivary Gland Neoplasms - pathology Salivary Glands - pathology Sensitivity and Specificity Ultrasonography, Interventional - methods Young Adult |
| title | Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors |
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