New closed-loop insulin systems
Advances in diabetes technologies have enabled the development of automated closed-loop insulin delivery systems. Several hybrid closed-loop systems have been commercialised, reflecting rapid transition of this evolving technology from research into clinical practice, where it is gradually transform...
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| Veröffentlicht in: | Diabetologia 2021-05, Vol.64 (5), p.1007-1015 |
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| creator | Boughton, Charlotte K. Hovorka, Roman |
| description | Advances in diabetes technologies have enabled the development of automated closed-loop insulin delivery systems. Several hybrid closed-loop systems have been commercialised, reflecting rapid transition of this evolving technology from research into clinical practice, where it is gradually transforming the management of type 1 diabetes in children and adults. In this review we consider the supporting evidence in terms of glucose control and quality of life for presently available closed-loop systems and those in development, including dual-hormone closed-loop systems. We also comment on alternative ‘do-it-yourself’ closed-loop systems. We remark on issues associated with clinical adoption of these approaches, including training provision, and consider limitations of presently available closed-loop systems and areas for future enhancements to further improve outcomes and reduce the burden of diabetes management.
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| doi_str_mv | 10.1007/s00125-021-05391-w |
| format | Article |
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Several hybrid closed-loop systems have been commercialised, reflecting rapid transition of this evolving technology from research into clinical practice, where it is gradually transforming the management of type 1 diabetes in children and adults. In this review we consider the supporting evidence in terms of glucose control and quality of life for presently available closed-loop systems and those in development, including dual-hormone closed-loop systems. We also comment on alternative ‘do-it-yourself’ closed-loop systems. We remark on issues associated with clinical adoption of these approaches, including training provision, and consider limitations of presently available closed-loop systems and areas for future enhancements to further improve outcomes and reduce the burden of diabetes management.
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| subjects | Adult Blood Glucose - analysis Blood Glucose - metabolism Blood Glucose Self-Monitoring - instrumentation Blood Glucose Self-Monitoring - trends Child Closed loop systems Diabetes Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Human Physiology Humans Insulin Insulin - administration & dosage Insulin - adverse effects Insulin 100 – celebrating 100 years of insulin Insulin Infusion Systems Internal Medicine Inventions - trends Manufacturers representatives Medicine Medicine & Public Health Metabolic Diseases Pancreas, Artificial - supply & distribution Pancreas, Artificial - trends Quality of life Review |
| title | New closed-loop insulin systems |
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