Modulation by Ozone Therapy of Oxidative Stress in Chemotherapy-Induced Peripheral Neuropathy: The Background for a Randomized Clinical Trial

(1) Background: Chemotherapy-induced peripheral neuropathy (CIPN) decreases the quality of life of patients and can lead to a dose reduction and/or the interruption of chemotherapy treatment, limiting its effectiveness. Potential pathophysiological mechanisms involved in the pathogenesis of CIPN inc...

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Veröffentlicht in:	International journal of molecular sciences 2021-03, Vol.22 (6), p.2802
Hauptverfasser:	Clavo, Bernardino, Martínez-Sánchez, Gregorio, Rodríguez-Esparragón, Francisco, Rodríguez-Abreu, Delvys, Galván, Saray, Aguiar-Bujanda, David, Díaz-Garrido, Juan A, Cañas, Silvia, Torres-Mata, Laura B, Fabelo, Himar, Téllez, Teresa, Santana-Rodríguez, Norberto, Fernández-Pérez, Leandro, Marrero-Callico, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents - therapeutic use Antineoplastic Agents - adverse effects Antioxidants Antioxidants - therapeutic use Apoptosis Bortezomib Cancer therapies Chemotherapy Clinical trials Cytokines Dehydrogenases Deoxyribonucleic acid DNA DNA damage DNA repair Drugs Free radicals Health services Humans Immunology Inflammation Inflammatory response Kinases Lipid peroxidation Metabolism Mitochondria Mitochondrial DNA Neoplasms - drug therapy Oxidation Oxidative stress Oxidative Stress - drug effects Ozone Ozone - therapeutic use Pain Pathogenesis Peripheral Nervous System Diseases - chemically induced Peripheral Nervous System Diseases - prevention & control Peripheral neuropathy Phosphorylation Physiology Platinum Proteins Quality of Life Randomized Controlled Trials as Topic Review Signal transduction Taxanes
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