Plk4 triggers autonomous de novo centriole biogenesis and maturation

Centrioles form centrosomes and cilia. In most proliferating cells, centrioles assemble through canonical duplication, which is spatially, temporally, and numerically regulated by the cell cycle and the presence of mature centrioles. However, in certain cell types, centrioles assemble de novo, yet b...

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Veröffentlicht in:	The Journal of cell biology 2021-05, Vol.220 (5), p.1
Hauptverfasser:	Nabais, Catarina, Pessoa, Delphine, de-Carvalho, Jorge, van Zanten, Thomas, Duarte, Paulo, Mayor, Satyajit, Carneiro, Jorge, Telley, Ivo A, Bettencourt-Dias, Mónica
Format:	Artikel
Sprache:	eng
Schlagworte:	Assembly Biosynthesis Cell cycle Centrioles Centrosomes Cilia Critical components Cytoskeleton Development Explants Kinases Polo-like kinase Reproduction (copying) Tubulin
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