Hepatitis A susceptibility parallels high COVID-19 mortality
COVID-19 has become the biggest health problem of this century. It has been hypothesized that immunity against hepatitis A virus (HAV) may provide protection from COVID- 19. As of 10June 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead. This data was...
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| Veröffentlicht in: | TURKISH JOURNAL OF MEDICAL SCIENCES 2021-02, Vol.51 (1), p.382-384 |
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| container_title | TURKISH JOURNAL OF MEDICAL SCIENCES |
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| creator | Sarialioğlu, Faik Belen, Fatma Burcu Hayran, Kadir Mutlu |
| description | COVID-19 has become the biggest health problem of this century. It has been hypothesized that immunity against
hepatitis A virus (HAV) may provide protection from COVID- 19.
As of 10June 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead. This data was combined with the World Health Organization susceptibility classification on the worldwide prevalence of HAV, and the relationship between HAV susceptibility and COVID-19 mortality were analyzed.
When the data from 213 countries were analyzed, it was found that there was a significant increasing trend in COVID-19 mortality rates by HAV susceptibility (P |
| doi_str_mv | 10.3906/sag-2007-133 |
| format | Article |
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hepatitis A virus (HAV) may provide protection from COVID- 19.
As of 10June 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead. This data was combined with the World Health Organization susceptibility classification on the worldwide prevalence of HAV, and the relationship between HAV susceptibility and COVID-19 mortality were analyzed.
When the data from 213 countries were analyzed, it was found that there was a significant increasing trend in COVID-19 mortality rates by HAV susceptibility (P <0.001). Using a cut-off of 200/million population, the mortality risk associated with living in a more susceptible country (medium/high) was 27.8 times higher (95% CI for OR: 3.6–213.2)
The results of this study showed that, despite confounding factors in different countries, hepatitis A susceptibility of the population may have been correlated with COVID-19 mortality. This observation needs to be confirmed by further studies.</description><identifier>ISSN: 1303-6165</identifier><identifier>ISSN: 1300-0144</identifier><identifier>EISSN: 1303-6165</identifier><identifier>DOI: 10.3906/sag-2007-133</identifier><identifier>PMID: 32718125</identifier><language>eng</language><publisher>Turkey: The Scientific and Technological Research Council of Turkey</publisher><subject>COVID-19 - immunology ; COVID-19 - mortality ; Disease Susceptibility - epidemiology ; Disease Susceptibility - immunology ; Hepatitis A - epidemiology ; Hepatitis A - immunology ; Hepatitis A virus - immunology ; Humans ; Middle Aged ; Risk Factors ; Ships</subject><ispartof>TURKISH JOURNAL OF MEDICAL SCIENCES, 2021-02, Vol.51 (1), p.382-384</ispartof><rights>Copyright © 2021 The Author(s) 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-3363ba0eab55a65c21a4321215f80ceabcaad8322a0cbfd5ffc7f9e0b4760af03</citedby><orcidid>0000-0002-8257-810X ; 0000-0003-2594-6794 ; 0000-0002-9278-6703</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991879/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991879/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32718125$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sarialioğlu, Faik</creatorcontrib><creatorcontrib>Belen, Fatma Burcu</creatorcontrib><creatorcontrib>Hayran, Kadir Mutlu</creatorcontrib><title>Hepatitis A susceptibility parallels high COVID-19 mortality</title><title>TURKISH JOURNAL OF MEDICAL SCIENCES</title><addtitle>Turk J Med Sci</addtitle><description>COVID-19 has become the biggest health problem of this century. It has been hypothesized that immunity against
hepatitis A virus (HAV) may provide protection from COVID- 19.
As of 10June 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead. This data was combined with the World Health Organization susceptibility classification on the worldwide prevalence of HAV, and the relationship between HAV susceptibility and COVID-19 mortality were analyzed.
When the data from 213 countries were analyzed, it was found that there was a significant increasing trend in COVID-19 mortality rates by HAV susceptibility (P <0.001). Using a cut-off of 200/million population, the mortality risk associated with living in a more susceptible country (medium/high) was 27.8 times higher (95% CI for OR: 3.6–213.2)
The results of this study showed that, despite confounding factors in different countries, hepatitis A susceptibility of the population may have been correlated with COVID-19 mortality. This observation needs to be confirmed by further studies.</description><subject>COVID-19 - immunology</subject><subject>COVID-19 - mortality</subject><subject>Disease Susceptibility - epidemiology</subject><subject>Disease Susceptibility - immunology</subject><subject>Hepatitis A - epidemiology</subject><subject>Hepatitis A - immunology</subject><subject>Hepatitis A virus - immunology</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Risk Factors</subject><subject>Ships</subject><issn>1303-6165</issn><issn>1300-0144</issn><issn>1303-6165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkE9LAzEQxYMotlZvnmU_gNEks9ndgAil_mmh0It6DbNp0ka23WWTFvrt3VIt9TTDzJv3hh8ht5w9gGLZY8AFFYzllAOckT4HBjTjmTw_6XvkKoRvxgSkUl2SHoicF1zIPnka2wajjz4kwyRsgrFN9KWvfNwlDbZYVbYKydIvlslo9jV5oVwlq7qNuFdckwuHVbA3v3VAPt9eP0ZjOp29T0bDKTVQpJECZFAis1hKiZk0gmMKggsuXcFMNzaI8wKEQGZKN5fOmdwpy8o0zxg6BgPyfPBtNuXKzo1dx-4z3bR-he1O1-j1_83aL_Wi3upcKV7kqjO4PxiYtg6hte54y5neU9QdRb2nqDuKnfzuNO8o_sMGP64_bzk</recordid><startdate>20210226</startdate><enddate>20210226</enddate><creator>Sarialioğlu, Faik</creator><creator>Belen, Fatma Burcu</creator><creator>Hayran, Kadir Mutlu</creator><general>The Scientific and Technological Research Council of Turkey</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8257-810X</orcidid><orcidid>https://orcid.org/0000-0003-2594-6794</orcidid><orcidid>https://orcid.org/0000-0002-9278-6703</orcidid></search><sort><creationdate>20210226</creationdate><title>Hepatitis A susceptibility parallels high COVID-19 mortality</title><author>Sarialioğlu, Faik ; Belen, Fatma Burcu ; Hayran, Kadir Mutlu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-3363ba0eab55a65c21a4321215f80ceabcaad8322a0cbfd5ffc7f9e0b4760af03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>COVID-19 - immunology</topic><topic>COVID-19 - mortality</topic><topic>Disease Susceptibility - epidemiology</topic><topic>Disease Susceptibility - immunology</topic><topic>Hepatitis A - epidemiology</topic><topic>Hepatitis A - immunology</topic><topic>Hepatitis A virus - immunology</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Risk Factors</topic><topic>Ships</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sarialioğlu, Faik</creatorcontrib><creatorcontrib>Belen, Fatma Burcu</creatorcontrib><creatorcontrib>Hayran, Kadir Mutlu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>TURKISH JOURNAL OF MEDICAL SCIENCES</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sarialioğlu, Faik</au><au>Belen, Fatma Burcu</au><au>Hayran, Kadir Mutlu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatitis A susceptibility parallels high COVID-19 mortality</atitle><jtitle>TURKISH JOURNAL OF MEDICAL SCIENCES</jtitle><addtitle>Turk J Med Sci</addtitle><date>2021-02-26</date><risdate>2021</risdate><volume>51</volume><issue>1</issue><spage>382</spage><epage>384</epage><pages>382-384</pages><issn>1303-6165</issn><issn>1300-0144</issn><eissn>1303-6165</eissn><abstract>COVID-19 has become the biggest health problem of this century. It has been hypothesized that immunity against
hepatitis A virus (HAV) may provide protection from COVID- 19.
As of 10June 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead. This data was combined with the World Health Organization susceptibility classification on the worldwide prevalence of HAV, and the relationship between HAV susceptibility and COVID-19 mortality were analyzed.
When the data from 213 countries were analyzed, it was found that there was a significant increasing trend in COVID-19 mortality rates by HAV susceptibility (P <0.001). Using a cut-off of 200/million population, the mortality risk associated with living in a more susceptible country (medium/high) was 27.8 times higher (95% CI for OR: 3.6–213.2)
The results of this study showed that, despite confounding factors in different countries, hepatitis A susceptibility of the population may have been correlated with COVID-19 mortality. This observation needs to be confirmed by further studies.</abstract><cop>Turkey</cop><pub>The Scientific and Technological Research Council of Turkey</pub><pmid>32718125</pmid><doi>10.3906/sag-2007-133</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0002-8257-810X</orcidid><orcidid>https://orcid.org/0000-0003-2594-6794</orcidid><orcidid>https://orcid.org/0000-0002-9278-6703</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; TÜBİTAK Scientific Journals |
| subjects | COVID-19 - immunology COVID-19 - mortality Disease Susceptibility - epidemiology Disease Susceptibility - immunology Hepatitis A - epidemiology Hepatitis A - immunology Hepatitis A virus - immunology Humans Middle Aged Risk Factors Ships |
| title | Hepatitis A susceptibility parallels high COVID-19 mortality |
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