160 The Effect of Frailty and COVID-19 Infection on Clinical Outcomes in Older Adults—A Single Centre Retrospective Study

Abstract Introduction It was anticipated that the COVID-19 pandemic would put a strain on our healthcare system, disproportionately affecting older people. NICE guidance recommended using frailty scoring to support decision making around escalation of care. This study aimed to assess frailty, demogr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Age and ageing 2021-03, Vol.50 (Supplement_1), p.i12-i42
Hauptverfasser: Okuwoga, O, Mufti, S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page i42
container_issue Supplement_1
container_start_page i12
container_title Age and ageing
container_volume 50
creator Okuwoga, O
Mufti, S
description Abstract Introduction It was anticipated that the COVID-19 pandemic would put a strain on our healthcare system, disproportionately affecting older people. NICE guidance recommended using frailty scoring to support decision making around escalation of care. This study aimed to assess frailty, demographics and COVID-19 infection and to investigate how these related to outcomes of patients aged over 65 years admitted to hospital. Methods A single centre retrospective cohort study was carried out by reviewing the electronic health records of all admissions over 65 years. Data points collected included length of stay (LOS), frailty score using the Rockwood Clinical Frailty Scale (CFS) and mortality. Patients were stratified into COVID and non-COVID based on health records and into non-frail (CFS 1–4) and frail (CFS 5–9). Results A total of 257 patients admitted between 30th March and 30th April 2020 were included in the study (mean age 79 years, 43% female). 141 (54.9%) of patients were diagnosed with COVID-19 infection. 120 patients had CFS 1–4 and 136 has CFS 5–9. 1 patient did not have a frailty score due to insufficient information. 68 (26.8%) of all patients died during the admission. The relative risk (RR) of mortality of patients with coronavirus was 6.3 (95% CI 3.1–12.6, p 
doi_str_mv 10.1093/ageing/afab030.121
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7989626</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/ageing/afab030.121</oup_id><sourcerecordid>2518124727</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2361-cebb376043cf39efec8ecb723b2ce266a9ddaee9f33936a30fbf66bc9462b8c03</originalsourceid><addsrcrecordid>eNqNUdtKJDEQDbKCs-oP-BTwuTWXNt15EYZexx0QBtbLa0jSlTHSk8ymu4XBFz_CL9wvMcMMgm8LBUVVnTp1ioPQGSUXlEh-qZfgw_JSO20Izz1GD9CElqIuWM3LH2hCCGEFqZg8Qj_7_iWX9IqyCXqjguCHZ8A3zoEdcHR4lrTvhg3WocXN4mn-q6ASz8N27GPAOZrOB291hxfjYOMKeuwDXnQtJDxtx27o_71_TPF9VtQBbiAMCfAfGFLs11uSV8D3w9huTtCh010Pp_t8jB5nNw_N7-JucTtvpneFZVzQwoIxvBKk5NZxCVlHDdZUjBtmgQmhZdtqAOk4l1xoTpxxQhgrS8FMbQk_Rtc73vVoVtDarSDdqXXyK502Kmqvvk-Cf1bL-KoqWUvBRCY43xOk-HeEflAvcUwha1bsitaUlRWrMortUDY_2idwXxcoUVuX1M4ltXdJZZfyUrFbiuP6f_CfhB2ZZw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2518124727</pqid></control><display><type>article</type><title>160 The Effect of Frailty and COVID-19 Infection on Clinical Outcomes in Older Adults—A Single Centre Retrospective Study</title><source>Applied Social Sciences Index &amp; Abstracts (ASSIA)</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Okuwoga, O ; Mufti, S</creator><creatorcontrib>Okuwoga, O ; Mufti, S</creatorcontrib><description>Abstract Introduction It was anticipated that the COVID-19 pandemic would put a strain on our healthcare system, disproportionately affecting older people. NICE guidance recommended using frailty scoring to support decision making around escalation of care. This study aimed to assess frailty, demographics and COVID-19 infection and to investigate how these related to outcomes of patients aged over 65 years admitted to hospital. Methods A single centre retrospective cohort study was carried out by reviewing the electronic health records of all admissions over 65 years. Data points collected included length of stay (LOS), frailty score using the Rockwood Clinical Frailty Scale (CFS) and mortality. Patients were stratified into COVID and non-COVID based on health records and into non-frail (CFS 1–4) and frail (CFS 5–9). Results A total of 257 patients admitted between 30th March and 30th April 2020 were included in the study (mean age 79 years, 43% female). 141 (54.9%) of patients were diagnosed with COVID-19 infection. 120 patients had CFS 1–4 and 136 has CFS 5–9. 1 patient did not have a frailty score due to insufficient information. 68 (26.8%) of all patients died during the admission. The relative risk (RR) of mortality of patients with coronavirus was 6.3 (95% CI 3.1–12.6, p &lt; 0.0001). The RR of mortality for frail patients compared to the non-frail was 2.1 (95% CI 1.3–3.2, p = 0.002). The median LOS for patients with COVID-19 was 5 days, compared to 4 days for patients who did not have coronavirus. Frailty did not predict longer admission, with median LOS of 5 days for both non-frail and frail patients. Conclusion The results demonstrated in this study show that COVID-19 infection and frailty were significantly associated with increased mortality in older patients. This validates the continued use of frailty scoring of older patients on admission to support care planning.</description><identifier>ISSN: 0002-0729</identifier><identifier>EISSN: 1468-2834</identifier><identifier>DOI: 10.1093/ageing/afab030.121</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Abstracts ; Care plans ; Clinical outcomes ; Cohort analysis ; Computerized medical records ; Coronaviridae ; Coronaviruses ; COVID-19 ; Decision making ; Demography ; Electronic medical records ; Frail ; Frailty ; Health records ; Hospitalization ; Infections ; Length of stay ; Mortality ; Older people ; Pandemics ; Patients ; Posters Scientific Presentation: Other (Other Medical Condition) ; Risk factors</subject><ispartof>Age and ageing, 2021-03, Vol.50 (Supplement_1), p.i12-i42</ispartof><rights>The Author(s) 2021. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com 2021</rights><rights>The Author(s) 2021. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,1578,27901,27902,30976</link.rule.ids></links><search><creatorcontrib>Okuwoga, O</creatorcontrib><creatorcontrib>Mufti, S</creatorcontrib><title>160 The Effect of Frailty and COVID-19 Infection on Clinical Outcomes in Older Adults—A Single Centre Retrospective Study</title><title>Age and ageing</title><description>Abstract Introduction It was anticipated that the COVID-19 pandemic would put a strain on our healthcare system, disproportionately affecting older people. NICE guidance recommended using frailty scoring to support decision making around escalation of care. This study aimed to assess frailty, demographics and COVID-19 infection and to investigate how these related to outcomes of patients aged over 65 years admitted to hospital. Methods A single centre retrospective cohort study was carried out by reviewing the electronic health records of all admissions over 65 years. Data points collected included length of stay (LOS), frailty score using the Rockwood Clinical Frailty Scale (CFS) and mortality. Patients were stratified into COVID and non-COVID based on health records and into non-frail (CFS 1–4) and frail (CFS 5–9). Results A total of 257 patients admitted between 30th March and 30th April 2020 were included in the study (mean age 79 years, 43% female). 141 (54.9%) of patients were diagnosed with COVID-19 infection. 120 patients had CFS 1–4 and 136 has CFS 5–9. 1 patient did not have a frailty score due to insufficient information. 68 (26.8%) of all patients died during the admission. The relative risk (RR) of mortality of patients with coronavirus was 6.3 (95% CI 3.1–12.6, p &lt; 0.0001). The RR of mortality for frail patients compared to the non-frail was 2.1 (95% CI 1.3–3.2, p = 0.002). The median LOS for patients with COVID-19 was 5 days, compared to 4 days for patients who did not have coronavirus. Frailty did not predict longer admission, with median LOS of 5 days for both non-frail and frail patients. Conclusion The results demonstrated in this study show that COVID-19 infection and frailty were significantly associated with increased mortality in older patients. This validates the continued use of frailty scoring of older patients on admission to support care planning.</description><subject>Abstracts</subject><subject>Care plans</subject><subject>Clinical outcomes</subject><subject>Cohort analysis</subject><subject>Computerized medical records</subject><subject>Coronaviridae</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Decision making</subject><subject>Demography</subject><subject>Electronic medical records</subject><subject>Frail</subject><subject>Frailty</subject><subject>Health records</subject><subject>Hospitalization</subject><subject>Infections</subject><subject>Length of stay</subject><subject>Mortality</subject><subject>Older people</subject><subject>Pandemics</subject><subject>Patients</subject><subject>Posters Scientific Presentation: Other (Other Medical Condition)</subject><subject>Risk factors</subject><issn>0002-0729</issn><issn>1468-2834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><recordid>eNqNUdtKJDEQDbKCs-oP-BTwuTWXNt15EYZexx0QBtbLa0jSlTHSk8ymu4XBFz_CL9wvMcMMgm8LBUVVnTp1ioPQGSUXlEh-qZfgw_JSO20Izz1GD9CElqIuWM3LH2hCCGEFqZg8Qj_7_iWX9IqyCXqjguCHZ8A3zoEdcHR4lrTvhg3WocXN4mn-q6ASz8N27GPAOZrOB291hxfjYOMKeuwDXnQtJDxtx27o_71_TPF9VtQBbiAMCfAfGFLs11uSV8D3w9huTtCh010Pp_t8jB5nNw_N7-JucTtvpneFZVzQwoIxvBKk5NZxCVlHDdZUjBtmgQmhZdtqAOk4l1xoTpxxQhgrS8FMbQk_Rtc73vVoVtDarSDdqXXyK502Kmqvvk-Cf1bL-KoqWUvBRCY43xOk-HeEflAvcUwha1bsitaUlRWrMortUDY_2idwXxcoUVuX1M4ltXdJZZfyUrFbiuP6f_CfhB2ZZw</recordid><startdate>20210316</startdate><enddate>20210316</enddate><creator>Okuwoga, O</creator><creator>Mufti, S</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>5PM</scope></search><sort><creationdate>20210316</creationdate><title>160 The Effect of Frailty and COVID-19 Infection on Clinical Outcomes in Older Adults—A Single Centre Retrospective Study</title><author>Okuwoga, O ; Mufti, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2361-cebb376043cf39efec8ecb723b2ce266a9ddaee9f33936a30fbf66bc9462b8c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Abstracts</topic><topic>Care plans</topic><topic>Clinical outcomes</topic><topic>Cohort analysis</topic><topic>Computerized medical records</topic><topic>Coronaviridae</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Decision making</topic><topic>Demography</topic><topic>Electronic medical records</topic><topic>Frail</topic><topic>Frailty</topic><topic>Health records</topic><topic>Hospitalization</topic><topic>Infections</topic><topic>Length of stay</topic><topic>Mortality</topic><topic>Older people</topic><topic>Pandemics</topic><topic>Patients</topic><topic>Posters Scientific Presentation: Other (Other Medical Condition)</topic><topic>Risk factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okuwoga, O</creatorcontrib><creatorcontrib>Mufti, S</creatorcontrib><collection>CrossRef</collection><collection>Applied Social Sciences Index &amp; Abstracts (ASSIA)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Age and ageing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okuwoga, O</au><au>Mufti, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>160 The Effect of Frailty and COVID-19 Infection on Clinical Outcomes in Older Adults—A Single Centre Retrospective Study</atitle><jtitle>Age and ageing</jtitle><date>2021-03-16</date><risdate>2021</risdate><volume>50</volume><issue>Supplement_1</issue><spage>i12</spage><epage>i42</epage><pages>i12-i42</pages><issn>0002-0729</issn><eissn>1468-2834</eissn><abstract>Abstract Introduction It was anticipated that the COVID-19 pandemic would put a strain on our healthcare system, disproportionately affecting older people. NICE guidance recommended using frailty scoring to support decision making around escalation of care. This study aimed to assess frailty, demographics and COVID-19 infection and to investigate how these related to outcomes of patients aged over 65 years admitted to hospital. Methods A single centre retrospective cohort study was carried out by reviewing the electronic health records of all admissions over 65 years. Data points collected included length of stay (LOS), frailty score using the Rockwood Clinical Frailty Scale (CFS) and mortality. Patients were stratified into COVID and non-COVID based on health records and into non-frail (CFS 1–4) and frail (CFS 5–9). Results A total of 257 patients admitted between 30th March and 30th April 2020 were included in the study (mean age 79 years, 43% female). 141 (54.9%) of patients were diagnosed with COVID-19 infection. 120 patients had CFS 1–4 and 136 has CFS 5–9. 1 patient did not have a frailty score due to insufficient information. 68 (26.8%) of all patients died during the admission. The relative risk (RR) of mortality of patients with coronavirus was 6.3 (95% CI 3.1–12.6, p &lt; 0.0001). The RR of mortality for frail patients compared to the non-frail was 2.1 (95% CI 1.3–3.2, p = 0.002). The median LOS for patients with COVID-19 was 5 days, compared to 4 days for patients who did not have coronavirus. Frailty did not predict longer admission, with median LOS of 5 days for both non-frail and frail patients. Conclusion The results demonstrated in this study show that COVID-19 infection and frailty were significantly associated with increased mortality in older patients. This validates the continued use of frailty scoring of older patients on admission to support care planning.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><doi>10.1093/ageing/afab030.121</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0002-0729
ispartof Age and ageing, 2021-03, Vol.50 (Supplement_1), p.i12-i42
issn 0002-0729
1468-2834
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7989626
source Applied Social Sciences Index & Abstracts (ASSIA); Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Abstracts
Care plans
Clinical outcomes
Cohort analysis
Computerized medical records
Coronaviridae
Coronaviruses
COVID-19
Decision making
Demography
Electronic medical records
Frail
Frailty
Health records
Hospitalization
Infections
Length of stay
Mortality
Older people
Pandemics
Patients
Posters Scientific Presentation: Other (Other Medical Condition)
Risk factors
title 160 The Effect of Frailty and COVID-19 Infection on Clinical Outcomes in Older Adults—A Single Centre Retrospective Study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T17%3A43%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=160%20The%20Effect%20of%20Frailty%20and%20COVID-19%20Infection%20on%20Clinical%20Outcomes%20in%20Older%20Adults%E2%80%94A%20Single%20Centre%20Retrospective%20Study&rft.jtitle=Age%20and%20ageing&rft.au=Okuwoga,%20O&rft.date=2021-03-16&rft.volume=50&rft.issue=Supplement_1&rft.spage=i12&rft.epage=i42&rft.pages=i12-i42&rft.issn=0002-0729&rft.eissn=1468-2834&rft_id=info:doi/10.1093/ageing/afab030.121&rft_dat=%3Cproquest_pubme%3E2518124727%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2518124727&rft_id=info:pmid/&rft_oup_id=10.1093/ageing/afab030.121&rfr_iscdi=true