Hyperbaric Oxygen Improves Cerebral Ischemia/Reperfusion Injury in Rats Probably via Inhibition of Autophagy Triggered by the Downregulation of Hypoxia-Inducing Factor-1 Alpha

Ischemic stroke, accompanied with high mortality and morbidity, may produce heavy economic burden to societies and families. Therefore, it is of great significance to explore effective therapies. Hyperbaric oxygen (HBO) is a noninvasive, nondrug treatment method that has been proved able to save isc...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021 (1), p.6615685-6615685
Hauptverfasser:	Wang, Cuiting, Niu, Feng, Ren, Ningna, Wang, Xiaokun, Zhong, Hequan, Zhu, Jie, Li, Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Apoptosis Autophagy Autophagy (Cytology) Care and treatment Carotid arteries Cerebral blood flow Cerebral infarction Development and progression Diagnosis Edema Genetic aspects Health aspects Hippocampus Hyperbaric oxygen Hyperbaric oxygenation Hypoxia Hypoxia-inducible factor 1a Infarction Ischemia Laboratory animals Medical research Metabolism Morbidity Occlusion Oxygen therapy Phagocytosis Physiological aspects Prevention Proteins Reperfusion Reperfusion injury Risk factors Stroke Stroke (Disease) TOR protein Transcription factors Traumatic brain injury Variance analysis Veins & arteries
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