Subtype Diagnosis of Sporadic Creutzfeldt–Jakob Disease with Diffusion Magnetic Resonance Imaging

Objective Sporadic Creutzfeldt–Jakob disease (sCJD) comprises several subtypes as defined by genetic and prion protein characteristics, which are associated with distinct clinical and pathological phenotypes. To date, no clinical test can reliably diagnose the subtype. We established two procedures...

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Veröffentlicht in:	Annals of neurology 2021-03, Vol.89 (3), p.560-572
Hauptverfasser:	Bizzi, Alberto, Pascuzzo, Riccardo, Blevins, Janis, Moscatelli, Marco E. M., Grisoli, Marina, Lodi, Raffaele, Doniselli, Fabio M., Castelli, Gianmarco, Cohen, Mark L., Stamm, Aymeric, Schonberger, Lawrence B., Appleby, Brian S., Gambetti, Pierluigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Autopsies Autopsy Brain - diagnostic imaging Clinical trials Creutzfeldt-Jakob disease Creutzfeldt-Jakob Syndrome - classification Creutzfeldt-Jakob Syndrome - diagnostic imaging Creutzfeldt-Jakob Syndrome - genetics Diagnosis Diffusion Magnetic Resonance Imaging Female Genotype Genotypes Humans Magnetic resonance imaging Male Medical imaging Middle Aged Neuroimaging Phenotypes Prion protein Prion Proteins - genetics Proteins
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