Randomized, Controlled Study of Opicapone in Japanese Parkinson's Patients with Motor Fluctuations

ABSTRACT Objectives This placebo‐controlled, randomized study evaluated the efficacy and safety of opicapone 25‐mg and 50‐mg tablets in Japanese levodopa‐treated patients with Parkinson's disease and motor fluctuations. Methods Japanese adults (n = 437, age 39–83 years) with Parkinson's di...

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Veröffentlicht in:	Movement disorders 2021-02, Vol.36 (2), p.415-423
Hauptverfasser:	Takeda, Atsushi, Takahashi, Ryosuke, Tsuboi, Yoshio, Nomoto, Masahiro, Maeda, Tetsuya, Nishimura, Akihisa, Yoshida, Kazuo, Hattori, Nobutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adverse events Aged Aged, 80 and over Antiparkinson Agents Double-Blind Method Dyskinesia Humans Japan Japanese Levodopa Levodopa - adverse effects Middle Aged Movement disorders Neurodegenerative diseases opicapone Oxadiazoles Parkinson Disease - drug therapy Parkinson's disease Placebos randomized controlled trial Regular Issue Statistical analysis Tablets Treatment Outcome United Kingdom
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