Ensemble docking to difficult targets in early‐stage drug discovery: Methodology and application to fibroblast growth factor 23

Ensemble docking is now commonly used in early‐stage in silico drug discovery and can be used to attack difficult problems such as finding lead compounds which can disrupt protein–protein interactions. We give an example of this methodology here, as applied to fibroblast growth factor 23 (FGF23), a...

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