The role of MET in chemotherapy resistance

Chemotherapy remains the mainstay of treatment in the majority of solid and haematological malignancies. Resistance to cytotoxic chemotherapy is a major clinical problem and substantial research is ongoing into potential methods of overcoming this resistance. One major target, the receptor tyrosine...

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Veröffentlicht in:	Oncogene 2021-03, Vol.40 (11), p.1927-1941
Hauptverfasser:	Wood, Georgina E., Hockings, Helen, Hilton, Danielle M., Kermorgant, Stéphanie
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1059/2326 631/67/1059/602 631/67/70 631/80/86/2368 Apoptosis c-Met protein Cancer Cell Biology Chemoresistance Chemotherapy Clinical trials Cytotoxicity Drug resistance Drug Resistance, Neoplasm - genetics Epidermal growth factor receptors Gene expression Genetic aspects Genotype Health aspects Human Genetics Humans Internal Medicine Medicine Medicine & Public Health Neoplasms - drug therapy Neoplasms - genetics Oncology Patient outcomes Protein-tyrosine kinase receptors Proteomics Proto-Oncogene Proteins c-met - genetics Review Review Article
Online-Zugang:	Volltext
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