Development and evaluation of a high performance T1‐weighted brain template for use in studies on older adults
Τhe accuracy of template‐based neuroimaging investigations depends on the template's image quality and representativeness of the individuals under study. Yet a thorough, quantitative investigation of how available standardized and study‐specific T1‐weighted templates perform in studies on older...
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| Veröffentlicht in: | Human brain mapping 2021-04, Vol.42 (6), p.1758-1776 |
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| creator | Ridwan, Abdur Raquib Niaz, Mohammad Rakeen Wu, Yingjuan Qi, Xiaoxiao Zhang, Shengwei Kontzialis, Marinos Javierre‐Petit, Carles Tazwar, Mahir Bennett, David A. Yang, Yongyi Arfanakis, Konstantinos |
| description | Τhe accuracy of template‐based neuroimaging investigations depends on the template's image quality and representativeness of the individuals under study. Yet a thorough, quantitative investigation of how available standardized and study‐specific T1‐weighted templates perform in studies on older adults has not been conducted. The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template (a) exhibited high image sharpness, (b) provided higher inter‐subject spatial normalization accuracy and (c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, (d) had similar performance to that of study‐specific templates constructed with the same methodology, and (e) was highly representative of the older adult brain.
The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template a) exhibited high image sharpness, b) provided higher inter‐subject spatial normalization accuracy and c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, d) had similar performance to that of study‐specific templates constructed with the same methodology, and e) was highly representative of the older adult brain. |
| doi_str_mv | 10.1002/hbm.25327 |
| format | Article |
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The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template a) exhibited high image sharpness, b) provided higher inter‐subject spatial normalization accuracy and c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, d) had similar performance to that of study‐specific templates constructed with the same methodology, and e) was highly representative of the older adult brain.</description><identifier>ISSN: 1065-9471</identifier><identifier>EISSN: 1097-0193</identifier><identifier>DOI: 10.1002/hbm.25327</identifier><identifier>PMID: 33449398</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Adults ; Aged ; Aged, 80 and over ; Aging ; Brain ; Brain - diagnostic imaging ; Female ; Humans ; Image Processing, Computer-Assisted - methods ; Image Processing, Computer-Assisted - standards ; Image quality ; magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Magnetic Resonance Imaging - standards ; Male ; Medical imaging ; Neuroimaging ; Neuroimaging - methods ; Neuroimaging - standards ; Older people ; Sharpness ; spatial normalization ; template</subject><ispartof>Human brain mapping, 2021-04, Vol.42 (6), p.1758-1776</ispartof><rights>2020 The Authors. published by Wiley Periodicals LLC.</rights><rights>2020 The Authors. Human Brain Mapping published by Wiley Periodicals LLC.</rights><rights>2020. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4437-9012e2e2c62b6dbe9f3e087ef83d45ed46ef44c9df6c2e0241b36f9ce4a6cb523</citedby><cites>FETCH-LOGICAL-c4437-9012e2e2c62b6dbe9f3e087ef83d45ed46ef44c9df6c2e0241b36f9ce4a6cb523</cites><orcidid>0000-0001-9705-597X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978143/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978143/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1411,11541,27901,27902,45550,45551,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33449398$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ridwan, Abdur Raquib</creatorcontrib><creatorcontrib>Niaz, Mohammad Rakeen</creatorcontrib><creatorcontrib>Wu, Yingjuan</creatorcontrib><creatorcontrib>Qi, Xiaoxiao</creatorcontrib><creatorcontrib>Zhang, Shengwei</creatorcontrib><creatorcontrib>Kontzialis, Marinos</creatorcontrib><creatorcontrib>Javierre‐Petit, Carles</creatorcontrib><creatorcontrib>Tazwar, Mahir</creatorcontrib><creatorcontrib>Bennett, David A.</creatorcontrib><creatorcontrib>Yang, Yongyi</creatorcontrib><creatorcontrib>Arfanakis, Konstantinos</creatorcontrib><creatorcontrib>Alzheimer's Disease Neuroimaging Initiative</creatorcontrib><title>Development and evaluation of a high performance T1‐weighted brain template for use in studies on older adults</title><title>Human brain mapping</title><addtitle>Hum Brain Mapp</addtitle><description>Τhe accuracy of template‐based neuroimaging investigations depends on the template's image quality and representativeness of the individuals under study. Yet a thorough, quantitative investigation of how available standardized and study‐specific T1‐weighted templates perform in studies on older adults has not been conducted. The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template (a) exhibited high image sharpness, (b) provided higher inter‐subject spatial normalization accuracy and (c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, (d) had similar performance to that of study‐specific templates constructed with the same methodology, and (e) was highly representative of the older adult brain.
The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template a) exhibited high image sharpness, b) provided higher inter‐subject spatial normalization accuracy and c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, d) had similar performance to that of study‐specific templates constructed with the same methodology, and e) was highly representative of the older adult brain.</description><subject>Adults</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging</subject><subject>Brain</subject><subject>Brain - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Image Processing, Computer-Assisted - standards</subject><subject>Image quality</subject><subject>magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Magnetic Resonance Imaging - standards</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Neuroimaging</subject><subject>Neuroimaging - methods</subject><subject>Neuroimaging - standards</subject><subject>Older people</subject><subject>Sharpness</subject><subject>spatial normalization</subject><subject>template</subject><issn>1065-9471</issn><issn>1097-0193</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNp1kc1OFTEUxxuiAUQWvoBp4kYXA_2aj25MFBVIMG5g3XTaU25JZzq2M5ew8xF8Rp_EXi4SMTFdnOacX345J3-EXlFyRAlhx6t-OGI1Z-0O2qdEthWhkj_b_Ju6kqKle-hFzjeEUFoTuov2OBdCctnto-kTrCHEaYBxxnq0GNY6LHr2ccTRYY1X_nqFJ0gupkGPBvAl_fXj5y2U9gwW90n7Ec8wTEHPgAuFlwy49PK8WA8Zb0TBQsLaLmHOL9Fzp0OGw4d6gK6-fL48Oasuvp2en3y4qIwQvK0koQzKMw3rG9uDdBxI14LruBU1WNGAE8JI6xrDgDBBe944aUDoxvQ14wfo_dY7Lf0A1pT7kg5qSn7Q6U5F7dXTyehX6jquVSvbjgpeBG8fBCl-XyDPavDZQAh6hLhkxUTb1V1HCS3om3_Qm7iksZynWE0k41TWTaHebSmTYs4J3OMylKhNjqrkqO5zLOzrv7d_JP8EV4DjLXDrA9z936TOPn7dKn8D3AuqLw</recordid><startdate>20210415</startdate><enddate>20210415</enddate><creator>Ridwan, Abdur Raquib</creator><creator>Niaz, Mohammad Rakeen</creator><creator>Wu, Yingjuan</creator><creator>Qi, Xiaoxiao</creator><creator>Zhang, Shengwei</creator><creator>Kontzialis, Marinos</creator><creator>Javierre‐Petit, Carles</creator><creator>Tazwar, Mahir</creator><creator>Bennett, David A.</creator><creator>Yang, Yongyi</creator><creator>Arfanakis, Konstantinos</creator><general>John Wiley & Sons, Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7TK</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9705-597X</orcidid></search><sort><creationdate>20210415</creationdate><title>Development and evaluation of a high performance T1‐weighted brain template for use in studies on older adults</title><author>Ridwan, Abdur Raquib ; 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Yet a thorough, quantitative investigation of how available standardized and study‐specific T1‐weighted templates perform in studies on older adults has not been conducted. The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template (a) exhibited high image sharpness, (b) provided higher inter‐subject spatial normalization accuracy and (c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, (d) had similar performance to that of study‐specific templates constructed with the same methodology, and (e) was highly representative of the older adult brain.
The purpose of this work was to construct a high‐quality standardized T1‐weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study‐specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter‐group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state‐of‐the‐art spatial normalization of high‐quality data from 222 older adults. It was shown that the new template a) exhibited high image sharpness, b) provided higher inter‐subject spatial normalization accuracy and c) allowed detection of smaller inter‐group morphometric differences compared to other standardized templates, d) had similar performance to that of study‐specific templates constructed with the same methodology, and e) was highly representative of the older adult brain.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>33449398</pmid><doi>10.1002/hbm.25327</doi><tpages>19</tpages><orcidid>https://orcid.org/0000-0001-9705-597X</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adults Aged Aged, 80 and over Aging Brain Brain - diagnostic imaging Female Humans Image Processing, Computer-Assisted - methods Image Processing, Computer-Assisted - standards Image quality magnetic resonance imaging Magnetic Resonance Imaging - methods Magnetic Resonance Imaging - standards Male Medical imaging Neuroimaging Neuroimaging - methods Neuroimaging - standards Older people Sharpness spatial normalization template |
| title | Development and evaluation of a high performance T1‐weighted brain template for use in studies on older adults |
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