Proton MR Spectroscopy in Wernicke Encephalopathy
Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and pr...
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| Veröffentlicht in: | American journal of neuroradiology : AJNR 2003-05, Vol.24 (5), p.952-955 |
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| container_title | American journal of neuroradiology : AJNR |
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| creator | Rugilo, Carlos A Uribe Roca, Marcela C Zurru, Maria C Capizzano, Aristides A Pontello, Gustavo A Gatto, Emilia M |
| description | Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy. |
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Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy.</description><identifier>ISSN: 0195-6108</identifier><identifier>EISSN: 1936-959X</identifier><identifier>PMID: 12748100</identifier><identifier>CODEN: AAJNDL</identifier><language>eng</language><publisher>Oak Brook, IL: Am Soc Neuroradiology</publisher><subject>Adult ; Aspartic Acid - analogs & derivatives ; Aspartic Acid - analysis ; Biological and medical sciences ; Brain ; Brain - pathology ; Brain Chemistry ; Diffusion Magnetic Resonance Imaging ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. 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Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy.</description><subject>Adult</subject><subject>Aspartic Acid - analogs & derivatives</subject><subject>Aspartic Acid - analysis</subject><subject>Biological and medical sciences</subject><subject>Brain</subject><subject>Brain - pathology</subject><subject>Brain Chemistry</subject><subject>Diffusion Magnetic Resonance Imaging</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Female</subject><subject>Humans</subject><subject>Lactic Acid - analysis</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Wernicke Encephalopathy - diagnosis</subject><subject>Wernicke Encephalopathy - metabolism</subject><issn>0195-6108</issn><issn>1936-959X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVj0tLxDAUhYMozjj6F6Qbl4U8mqZ3I8gwPmBE8YHuQppmptFOUpJq6b-34Ojo6i7Odz7O3UNTAixPgcPrPppiAjzNCS4m6CjGN4wxB0EP0YRQkRUE4yki98F33iW3D8lja3QXfNS-HRLrkhcTnNXvJlk4bdpaNb5VXT0co4OVaqI52d4Zer5cPM2v0-Xd1c38YpnWjNIuBQIVN4xwUVLMSmHKYqVzTAvGC20yhamoxnmgc0Yyg6k2QJhSOS00K7kGNkPn3972o9yYShvXBdXINtiNCoP0ysr_ibO1XPtPKUBwkYtRcPpX8Nv8eX4EzraAilo1q6CctnHHjZQASndcbdd1b4ORcaOaZtQS2fc9zSSXwCn7AoK2cR0</recordid><startdate>20030501</startdate><enddate>20030501</enddate><creator>Rugilo, Carlos A</creator><creator>Uribe Roca, Marcela C</creator><creator>Zurru, Maria C</creator><creator>Capizzano, Aristides A</creator><creator>Pontello, Gustavo A</creator><creator>Gatto, Emilia M</creator><general>Am Soc Neuroradiology</general><general>American Society of Neuroradiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>5PM</scope></search><sort><creationdate>20030501</creationdate><title>Proton MR Spectroscopy in Wernicke Encephalopathy</title><author>Rugilo, Carlos A ; Uribe Roca, Marcela C ; Zurru, Maria C ; Capizzano, Aristides A ; Pontello, Gustavo A ; Gatto, Emilia M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h322t-919d5e3157b203b7eb8fc6028358ce4a027d1959c6314e02ce913aa628c3b5c93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Aspartic Acid - analogs & derivatives</topic><topic>Aspartic Acid - analysis</topic><topic>Biological and medical sciences</topic><topic>Brain</topic><topic>Brain - pathology</topic><topic>Brain Chemistry</topic><topic>Diffusion Magnetic Resonance Imaging</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Female</topic><topic>Humans</topic><topic>Lactic Acid - analysis</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Wernicke Encephalopathy - diagnosis</topic><topic>Wernicke Encephalopathy - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rugilo, Carlos A</creatorcontrib><creatorcontrib>Uribe Roca, Marcela C</creatorcontrib><creatorcontrib>Zurru, Maria C</creatorcontrib><creatorcontrib>Capizzano, Aristides A</creatorcontrib><creatorcontrib>Pontello, Gustavo A</creatorcontrib><creatorcontrib>Gatto, Emilia M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of neuroradiology : AJNR</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rugilo, Carlos A</au><au>Uribe Roca, Marcela C</au><au>Zurru, Maria C</au><au>Capizzano, Aristides A</au><au>Pontello, Gustavo A</au><au>Gatto, Emilia M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Proton MR Spectroscopy in Wernicke Encephalopathy</atitle><jtitle>American journal of neuroradiology : AJNR</jtitle><addtitle>AJNR Am J Neuroradiol</addtitle><date>2003-05-01</date><risdate>2003</risdate><volume>24</volume><issue>5</issue><spage>952</spage><epage>955</epage><pages>952-955</pages><issn>0195-6108</issn><eissn>1936-959X</eissn><coden>AAJNDL</coden><abstract>Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy.</abstract><cop>Oak Brook, IL</cop><pub>Am Soc Neuroradiology</pub><pmid>12748100</pmid><tpages>4</tpages></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adult Aspartic Acid - analogs & derivatives Aspartic Acid - analysis Biological and medical sciences Brain Brain - pathology Brain Chemistry Diffusion Magnetic Resonance Imaging Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Female Humans Lactic Acid - analysis Magnetic Resonance Spectroscopy Medical sciences Nervous system (semeiology, syndromes) Neurology Wernicke Encephalopathy - diagnosis Wernicke Encephalopathy - metabolism |
| title | Proton MR Spectroscopy in Wernicke Encephalopathy |
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