The cytotoxicity and molecular mechanisms of the Clostridium perfringens NetB toxin

The necrotic enteritis toxin B-like (NetB) toxin secreted by Clostridium perfringens is a key virulence agent in the pathogenesis of avian necrotic enteritis, a disease that causes significant economic loss to the poultry industry worldwide. NetB was purified from Clostridium perfringens type G (CNE...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2021, Vol.83(2), pp.187-194
Hauptverfasser:	ISLAM, AKM Azharul, NAKATANI, Mitsuki, NAKAJIMA, Takayuki, KOHDA, Tomoko, MUKAMOTO, Masafumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Toxins - administration & dosage Bacterial Toxins - genetics Bacterial Toxins - toxicity Cell Line Cell membranes Chickens Cholesterol Clostridium Infections - etiology Clostridium Infections - microbiology Clostridium Infections - veterinary Clostridium perfringens Clostridium perfringens - metabolism Clostridium perfringens - pathogenicity Cytotoxicity Enteritis Enteritis - etiology Enteritis - microbiology Enteritis - veterinary Hepatocytes Immunoblotting Injections, Intraperitoneal - veterinary Japan Localization Molecular modelling Monomers necrotic enteritis necrotic enteritis toxin B-like Oligomerization Pathogenicity Poultry Diseases - etiology Poultry Diseases - microbiology Public Health Toxin B Virulence
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