Endovascular Stroke Treatment Today
The purpose of this study was to review current treatment options in acute ischemic stroke, focusing on the latest advances in the field of mechanical recanalization. These devices recently made available for endovascular intracranial thrombectomy show great potential in acute stroke treatments. Com...
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| Veröffentlicht in: | American journal of neuroradiology : AJNR 2011-02, Vol.32 (2), p.238-243 |
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| container_title | American journal of neuroradiology : AJNR |
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| creator | GRUNWALD, I. Q WAKHLOO, A. K ROFFI, M SIEVERT, H BUCHAN, A WALTER, S MOLYNEUX, A. J BYRNE, J. V NAGEL, S KÜHN, A. L PAPADAKIS, M FASSBENDER, K BALAMI, J. S |
| description | The purpose of this study was to review current treatment options in acute ischemic stroke, focusing on the latest advances in the field of mechanical recanalization. These devices recently made available for endovascular intracranial thrombectomy show great potential in acute stroke treatments. Compelling evidence of their recanalization efficacy comes from current mechanical embolectomy trials. In addition to allowing an extension of the therapeutic time window, mechanical recanalization devices can be used without adjuvant thrombolytic therapy, thus diminishing the intracranial bleeding risk. Therefore, these devices are particularly suitable in patients in whom thrombolytic therapy is contraindicated. IV and IA thrombolysis and bridging therapy are viable options in acute stroke treatment. Mechanical recanalization devices can potentially have a clinically relevant impact in the interventional treatment of stroke, but at the present time, a randomized study would be beneficial. |
| doi_str_mv | 10.3174/ajnr.A2346 |
| format | Article |
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Q ; WAKHLOO, A. K ; ROFFI, M ; SIEVERT, H ; BUCHAN, A ; WALTER, S ; MOLYNEUX, A. J ; BYRNE, J. V ; NAGEL, S ; KÜHN, A. L ; PAPADAKIS, M ; FASSBENDER, K ; BALAMI, J. S</creator><creatorcontrib>GRUNWALD, I. Q ; WAKHLOO, A. K ; ROFFI, M ; SIEVERT, H ; BUCHAN, A ; WALTER, S ; MOLYNEUX, A. J ; BYRNE, J. V ; NAGEL, S ; KÜHN, A. L ; PAPADAKIS, M ; FASSBENDER, K ; BALAMI, J. S</creatorcontrib><description>The purpose of this study was to review current treatment options in acute ischemic stroke, focusing on the latest advances in the field of mechanical recanalization. These devices recently made available for endovascular intracranial thrombectomy show great potential in acute stroke treatments. Compelling evidence of their recanalization efficacy comes from current mechanical embolectomy trials. In addition to allowing an extension of the therapeutic time window, mechanical recanalization devices can be used without adjuvant thrombolytic therapy, thus diminishing the intracranial bleeding risk. Therefore, these devices are particularly suitable in patients in whom thrombolytic therapy is contraindicated. IV and IA thrombolysis and bridging therapy are viable options in acute stroke treatment. Mechanical recanalization devices can potentially have a clinically relevant impact in the interventional treatment of stroke, but at the present time, a randomized study would be beneficial.</description><identifier>ISSN: 0195-6108</identifier><identifier>EISSN: 1936-959X</identifier><identifier>DOI: 10.3174/ajnr.A2346</identifier><identifier>PMID: 21233233</identifier><identifier>CODEN: AAJNDL</identifier><language>eng</language><publisher>Oak Brook, IL: American Society of Neuroradiology</publisher><subject>Acute Disease ; Biological and medical sciences ; Brain Ischemia - drug therapy ; Brain Ischemia - surgery ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Nervous system ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Review ; Stroke - drug therapy ; Stroke - surgery ; Thrombectomy ; Thrombolytic Therapy</subject><ispartof>American journal of neuroradiology : AJNR, 2011-02, Vol.32 (2), p.238-243</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © American Society of Neuroradiology 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-2d4859abe910d0808903e2c9f2666c9cf7cfc4688d5f1ae99994afc438245c033</citedby><cites>FETCH-LOGICAL-c439t-2d4859abe910d0808903e2c9f2666c9cf7cfc4688d5f1ae99994afc438245c033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7965694/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7965694/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,729,782,786,887,27931,27932,53798,53800</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23866238$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21233233$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>GRUNWALD, I. Q</creatorcontrib><creatorcontrib>WAKHLOO, A. K</creatorcontrib><creatorcontrib>ROFFI, M</creatorcontrib><creatorcontrib>SIEVERT, H</creatorcontrib><creatorcontrib>BUCHAN, A</creatorcontrib><creatorcontrib>WALTER, S</creatorcontrib><creatorcontrib>MOLYNEUX, A. J</creatorcontrib><creatorcontrib>BYRNE, J. V</creatorcontrib><creatorcontrib>NAGEL, S</creatorcontrib><creatorcontrib>KÜHN, A. L</creatorcontrib><creatorcontrib>PAPADAKIS, M</creatorcontrib><creatorcontrib>FASSBENDER, K</creatorcontrib><creatorcontrib>BALAMI, J. S</creatorcontrib><title>Endovascular Stroke Treatment Today</title><title>American journal of neuroradiology : AJNR</title><addtitle>AJNR Am J Neuroradiol</addtitle><description>The purpose of this study was to review current treatment options in acute ischemic stroke, focusing on the latest advances in the field of mechanical recanalization. These devices recently made available for endovascular intracranial thrombectomy show great potential in acute stroke treatments. Compelling evidence of their recanalization efficacy comes from current mechanical embolectomy trials. In addition to allowing an extension of the therapeutic time window, mechanical recanalization devices can be used without adjuvant thrombolytic therapy, thus diminishing the intracranial bleeding risk. Therefore, these devices are particularly suitable in patients in whom thrombolytic therapy is contraindicated. IV and IA thrombolysis and bridging therapy are viable options in acute stroke treatment. Mechanical recanalization devices can potentially have a clinically relevant impact in the interventional treatment of stroke, but at the present time, a randomized study would be beneficial.</description><subject>Acute Disease</subject><subject>Biological and medical sciences</subject><subject>Brain Ischemia - drug therapy</subject><subject>Brain Ischemia - surgery</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Nervous system</subject><subject>Radiodiagnosis. Nmr imagery. 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| subjects | Acute Disease Biological and medical sciences Brain Ischemia - drug therapy Brain Ischemia - surgery Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Nervous system Radiodiagnosis. Nmr imagery. Nmr spectrometry Review Stroke - drug therapy Stroke - surgery Thrombectomy Thrombolytic Therapy |
| title | Endovascular Stroke Treatment Today |
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