Correlation of automated volumetric analysis of brain MR imaging with cognitive impairment in a natural history study of mucopolysaccharidosis II

Reliable markers for predicting neurologic outcome in patients with MPS II are lacking. The purpose of this study is to explore whether quantitative volumetric measurements of brain MR imaging can be used to differentiate between MPS II patients with and without cognitive impairment. This MR imaging...

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Veröffentlicht in:	American journal of neuroradiology : AJNR 2010-08, Vol.31 (7), p.1319-1323
Hauptverfasser:	Fan, Zheng, Styner, M, Muenzer, J, Poe, M, Escolar, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Atrophy Brain Brain - pathology Child Child, Preschool Cognition Disorders - etiology Cognition Disorders - pathology Disease Progression Humans Longitudinal Studies Magnetic Resonance Imaging - methods Male Mucopolysaccharidosis II - complications Mucopolysaccharidosis II - pathology Predictive Value of Tests Regression Analysis Young Adult
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