MR Spectroscopy Findings in Early Stages of Motor Neuron Disease

Upper motor neuron degeneration varies in different phenotypes of MND. We used single-voxel MR spectroscopy of the primary motor cortex to detect corticomotoneuron degeneration and glial hyperactivity in different phenotypes of MND with a relatively short disease duration, contributing to further de...

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Veröffentlicht in:	American journal of neuroradiology : AJNR 2010-11, Vol.31 (10), p.1799-1806
Hauptverfasser:	VAN DER GRAAFF, M. M, LAVINI, C, AKKERMAN, E. M, MAJOIE, Ch. B, NEDERVEEN, A. J, ZWINDERMAN, A. H, BRUGMAN, F, VAN DEN BERG, L. H, DE JONG, J. M. B. V, DE VISSER, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Cohort Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Early Diagnosis Female Follow-Up Studies Functional Humans Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Spectroscopy - methods Magnetic Resonance Spectroscopy - standards Male Medical sciences Middle Aged Motor Cortex - metabolism Motor Neuron Disease - diagnosis Motor Neuron Disease - metabolism Motor Neurons - cytology Motor Neurons - metabolism Nervous system Neuroglia - cytology Neuroglia - metabolism Neurology Phenotype Prospective Studies Radiodiagnosis. Nmr imagery. Nmr spectrometry Reproducibility of Results ROC Curve
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